Results 141 to 150 of about 2,331,184 (299)

Melamine regulatory assessment for endocrine disruption

Environment International
Melamine has several domestic and industrial uses as a flame retardant or in the manufacture of melamine–formaldehyde resins. Based on available scientific literature data, the French Agency for Food, Environmental and Occupational Health & Safety ...
Isabelle Charron, Brigitte Le Magueresse-Battistoni, René Habert, Marie-Chantal Canivenc-Lavier, Sakina Mhaouty-Kodja, Cécile Michel-Caillet   +5 more
doaj   +1 more source

Turkey: Financial System Stability Assessment

IMF Staff Country Reports, 2007
This Financial System Stability Assessment on Turkey discusses macroeconomic development and trend in the financial system. The financial system does not appear to face major immediate threats, but vulnerabilities remain. Turkey remains dependent on capital inflows and thus on international investor sentiment.
openaire   +4 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Development of high efficiency opaque photocathodes for the Region 900 angstrom to 1200 angstrom [PDF]

Progress in the following three areas is reported: investigation of the basic properties of candidate photocathode materials; measurement of the quantum detection efficiency (QDE) of KCl, RbBr, and CsBr as a function of wavelength and incident angle; and
Lampton, M., Siegmund, O.
core   +1 more source

Rwanda: Financial System Stability Assessment

IMF Staff Country Reports, 2011
In this study, the processes involved in the financial stability of Rwanda after the global crisis are imparted. High growth and major risks included in macroeconomic stability are analyzed. In the case of the banking sector, the structure, performance, and competition of Rwandan banks are outlined. The steps to strengthen regulation and supervision of
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Voltage stability assessment and contingency ranking in power systems based on modern stability assessment index

Results in Engineering
Electric loads steadily increase each year due to economic and population expansion, placing electric systems close to their stability limits. Also, the electrical network is a sophisticated system with various control, protection devices, and power ...
Salah Mokred, Yifei Wang
doaj   +1 more source

Malaysia: Financial Sector Stability Assessment

IMF Staff Country Reports, 2013
This assessment is a review of the financial environment of Malaysia. Like many other Asian countries, Malaysia experienced financial distress in the late 1990s, but the country’s policy reforms have moved it to a successful economy. A ten-year financial plan (2001–10) by Bank Negara Malaysia restructured the financial sector.
openaire   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source