Results 81 to 90 of about 25,964 (155)

Principled Fourier Neural Operators for High‐Resolution Regional Ocean Modeling

open access: yesJournal of Geophysical Research: Machine Learning and Computation, Volume 3, Issue 2, April 2026.
Abstract Reliable and computationally efficient ocean state forecasts are essential for climate resilience, maritime safety, and science‐to‐decision applications. Growing demand has stimulated interest in machine learning approaches as scalable complements to traditional numerical models.
Vahidreza Jahanmard   +4 more
wiley   +1 more source

Plant-derived exosomes: an emerging delivery platform for cancer therapy. [PDF]

open access: yesJ Nanobiotechnology
Zhou Y   +8 more
europepmc   +1 more source

Data‐Driven Estimation of Time‐Variable Catchment Transit Time Distributions

open access: yesWater Resources Research, Volume 62, Issue 4, April 2026.
Abstract Transit Time Distributions (TTDs) are widely used to summarize catchment behavior and are useful for understanding solute transport processes. Most methods for estimating TTDs from tracer data involve imposing strong model assumptions, which may affect the results.
Quentin Duchemin   +3 more
wiley   +1 more source

Fast automated adjoints for spectral PDE solvers. [PDF]

open access: yesProc Natl Acad Sci U S A
Skene CS, Burns KJ.
europepmc   +1 more source

Integration of Physics‐Constrained Learning With Adversarial Autoencoders for Simultaneous Inference of Hydraulic Conductivity and Contaminant Sources

open access: yesWater Resources Research, Volume 62, Issue 4, April 2026.
Abstract Determining heterogeneous conductivity fields and reconstructing contaminant release histories in subsurface remediation often lead to a high‐dimensional inverse problem. To tackle this issue, researchers typically integrate model outputs with sparse and noisy measurements of hydraulic head and concentration.
Zhenjie Tang, Li He
wiley   +1 more source

Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 7, Page 1364-1389, April 2026.
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen   +2 more
wiley   +1 more source

Generative discovery of partial differential equations by learning from math handbooks. [PDF]

open access: yesNat Commun
Xu H   +7 more
europepmc   +1 more source

Functional divergence of protein kinase A regulatory subunit Iβ variants: the importance of N3A motifs in PKA regulation

open access: yesThe FEBS Journal, Volume 293, Issue 8, Page 2417-2434, April 2026.
The regulatory subunit RIβ of protein kinase A occurs in two variants that differ at residue 268 (A268 versus R268). This seemingly small substitution significantly changes cAMP sensitivity, basal kinase activity, and the dynamic behavior of the regulatory domains.
Maximilian Wallbott   +6 more
wiley   +1 more source

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