Results 61 to 70 of about 2,192 (177)

Applications of stability theory to ecological problems [PDF]

open access: yes, 2013
The goal of ecology is to investigate the interactions among organisms and their environment. However, ecological systems often exhibit complex dynamics. The application of mathematics to ecological problems has made tremendous progress over the years
Dagbovie, Ayawoa
core  

Advances in Dynamical Low-Rank Approximations for random PDEs and Data Assimilation [PDF]

open access: yes
In the context of Uncertainty Quantification, simulating high-dimensional stochastic dynamical systems remains a challenging task owing to the high computational cost they incur.
Trigo Trindade, Thomas Simon Spencer
core   +2 more sources

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter   +20 more
wiley   +1 more source

Some Results in Nonlinear PDEs: Large Deviations Problems, Nonlocal Operators, and Stability for Some Isoperimetric Problems [PDF]

open access: yes, 2016
This thesis is concerned with various problems arising in the study of nonlinear elliptic PDE. It is divided into three parts. In the first part we consider the short time behaviour of stochastic systems affected by a stochastic volatility evolving at a
Ghilli, Daria
core  

Compartmentalisation in cAMP signalling: A phase separation perspective

open access: yesBritish Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Design of unknown input observers for nonlinear systems with full and partial information [PDF]

open access: yes, 2016
The problem of designing Unknown Input Observers (UIOs) for nonlinear systems is approached in this paper, in the cases of full and partial information. In the former, it is shown that the construction hinges upon the solution of a system of first-order ...
Cristofaro, A   +7 more
core   +1 more source

Prediction-based control of linear input-delay system subject to state-dependent state delay – Application to suppression of mechanical vibrations in drilling [PDF]

open access: yes, 2016
International audienceIn this paper, we consider linear dynamics subject to a distributed state-dependent delay and a pointwise input-delay. We propose a prediction-based controller which exponentially stabilizes the plant. The controller design is based
Bresch-Pietri, Delphine   +1 more
core   +2 more sources

Non‐canonical PKG1 regulation in cardiovascular health and disease

open access: yesBritish Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Stabilization of Pulses by Diffusion [PDF]

open access: yes, 2007
Stationary and traveling pulses appear generically in the dynamics generated by nonlinear partial differential equations (PDEs) of evolution type.
A. Doelman
core  

New biosensors and transgenic mice for multiplex cGMP imaging

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a versatile second messenger that is important for human (patho‐)physiology and pharmacotherapy. Live‐cell imaging of cGMP with biosensors allows to elucidate its spatiotemporal dynamics in real time under close‐to‐native conditions. However, to monitor two separate cGMP pools or cGMP/cAMP
Markus Wolters   +6 more
wiley   +1 more source

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