Results 81 to 90 of about 2,776,634 (316)

A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls, Abel Torres‐Espin, Marc Tormo, Laura Martínez‐Escardó, Núria Bonet, Ferran Casals, Xavier Navarro, Víctor J. Yuste, Esther Udina, Jordi Bruna   +9 more
wiley   +1 more source

Linear functional state bounding for positive singular systems with unbounded delay and disturbances varying within a bounded set

IET Control Theory & Applications, 2021
In this paper, the linear functional state bounding problem, which is considered in [25], is extended to the singular system with unbounded delay.
Nguyen Huu Sau
doaj   +1 more source

Stabilization of infinite-dimensional linear control systems by POD reduced-order Riccati feedback [PDF]

arXiv, 2019
There exist many ways to stabilize an infinite-dimensional linear autonomous control systems when it is possible. Anyway, finding an exponentially stabilizing feedback control that is as simple as possible may be a challenge. The Riccati theory provides a nice feedback control but may be computationally demanding when considering a discretization ...
arxiv  

On forward invariance in Lyapunov stability theorem for local stability [PDF]

arXiv, 2020
Forward invariance of a basin of attraction is often overlooked when using a Lyapunov stability theorem to prove local stability; even if the Lyapunov function decreases monotonically in a neighborhood of an equilibrium, the dynamic may escape from this neighborhood.
arxiv  

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

Molecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina, Viviana Bazan, Nadia Barraco, Simona Taverna, Mauro Manno, Samuele Raccosta, Anna Paola Carreca, Marco Bono, Tancredi Didier Bazan Russo, Francesco Pepe, Pasquale Pisapia, Lorena Incorvaia, Giuseppe Badalamenti, Giancarlo Troncone, Umberto Malapelle, Daniele Santini, Antonio Russo, Antonio Galvano   +17 more
wiley   +1 more source

Fault detection for asynchronous T–S fuzzy networked Markov jump systems with new event‐triggered scheme

IET Control Theory & Applications, 2021
In this article, an adaptive event‐triggered fault detection problem for the asynchronous Takagi–Sugeno fuzzy networked Markov jump systems is investigated based upon the time‐varying delays. The purpose of designing a fault detection filter is to detect
Muhammad Shamrooz Aslam, Qianmu Li, Jun Hou   +2 more
doaj   +1 more source

The Controller Generated from Noise Can Be Lyapunuov Stable: A Controller Stabilized Method [PDF]

arXiv, 2019
Aiming at the difficulty of stability analysis in practical application of existing control methods, a controller strategy based on lyapunov stability theory is proposed to realize stable control for any control method. In order to illustrate the effectiveness of this control scheme, this paper lists two different lyapunov functions to test the control
arxiv  

Switching control for incremental stabilization of nonlinear systems via contraction theory [PDF]

2016 European Control Conference (ECC), 2016
In this paper we present a switching control strategy to incrementally stabilize a class of nonlinear dynamical systems. Exploiting recent results on contraction analysis of switched Filippov systems derived using regularization, sufficient conditions are presented to prove incremental stability of the closed-loop system.
Di Bernardo M., Fiore D.
openaire   +5 more sources

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source