Results 61 to 70 of about 224,529 (264)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Intelligent control of a single‐link flexible manipulator using sliding modes and artificial neural networks

open access: yesElectronics Letters, 2021
This letter presents a new intelligent control scheme for the accurate trajectory tracking of flexible link manipulators. The proposed approach is mainly based on a sliding mode controller for underactuated systems with an embedded artificial neural ...
Gabriel da Silva Lima   +3 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Linear functional state bounding for positive singular systems with unbounded delay and disturbances varying within a bounded set

open access: yesIET Control Theory & Applications, 2021
In this paper, the linear functional state bounding problem, which is considered in [25], is extended to the singular system with unbounded delay.
Nguyen Huu Sau
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The occurrence mechanism and damping method of ultra‐low‐frequency oscillations

open access: yesIET Renewable Power Generation, 2021
The ultra‐low‐frequency oscillation (ULFO) problem has reappeared in China recently. Although the hydraulic generator is supposed to have a strong connection to this problem, the conditions for ULFO appearance and detailed reasons are not clear yet.
Peng Wang   +6 more
doaj   +1 more source

Multiplier theory for stability analysis of anti-windup control systems [PDF]

open access: yesProceedings of 1995 34th IEEE Conference on Decision and Control, 1999
The paper studies a general framework for analyzing stability of anti-windup bumpless transfer control systems. The authors apply the passivity theorem for deriving sufficient conditions of stability for a class of input nonlinearities.
Mayuresh V. Kothare, Manfred Morari
openaire   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Cooperative control of large flexible space structure by two planar robots

open access: yesIET Control Theory & Applications, 2021
This study discusses a cooperative control problem of a flexible beam by two planar space robots. The goal is to control the position and orientation of the flexible structure and robots, and to suppress the vibration of the flexible structure.
Yuta Kawai   +2 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

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