Results 51 to 60 of about 637,963 (247)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

A novel design of fractional Meyer wavelet neural networks with application to the nonlinear singular fractional Lane-Emden systems

Alexandria Engineering Journal, 2021
In this study, a novel stochastic computational frameworks based on fractional Meyer wavelet artificial neural network (FMW-ANN) is designed for nonlinear-singular fractional Lane-Emden (NS-FLE) differential equation.
Zulqurnain Sabir, Muhammad Asif Zahoor Raja, Juan L.G. Guirao, Muhammad Shoaib   +3 more
doaj   +1 more source

Relation between the eigenfrequencies of Bogoliubov excitations of Bose-Einstein condensates and the eigenvalues of the Jacobian in a time-dependent variational approach

, 2012
We study the relation between the eigenfrequencies of the Bogoliubov excitations of Bose-Einstein condensates, and the eigenvalues of the Jacobian stability matrix in a variational approach which maps the Gross-Pitaevskii equation to a system of ...
G. B. Arfken, Günter Wunner, Jörg Main, L. P. Pitaevskii, M. J. D. Powell, Manuel Kreibich, W. J. Thompson   +6 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Asymptotic analysis of numerical wave propagation in finite difference equations [PDF]

, 1983
March 1983Also issued as: Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Aeronautics and Astronautics, 1983Includes bibliographical references (page 134)An asymptotic technique is developed for analysing the propagation and dissipation of
Giles, M. (Michael), Thompkins, William T.   +1 more
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Existence and Global Exponential Stability of Pseudo Almost Periodic Solutions for Neutral Type Quaternion-Valued Neural Networks with Delays in the Leakage Term on Time Scales

Complexity, 2017
We propose a class of neutral type quaternion-valued neural networks with delays in the leakage term on time scales that can unify the discrete-time and the continuous-time neural networks. In order to avoid the difficulty brought by the noncommutativity
Yongkun Li, Xiaofang Meng
doaj   +1 more source

Stability of self-consistent solutions for the Hubbard model at intermediate and strong coupling

, 1999
We present a general framework how to investigate stability of solutions within a single self-consistent renormalization scheme being a parquet-type extension of the Baym-Kadanoff construction of conserving approximations.
A. Georges, A. Georges, A.A. Abrikosov, A.D. Jackson, B. Roulet, C. De Dominicis, C. De Dominicis, C. De Dominicis, C. De Dominicis, D.R. Hamann, E. Dagotto, E.H. Lieb, G. Baym, G. Baym, G. Moeller, J. Schlipf, M. Jarrell, M. Vilk, N.E. Bickers, N.E. Bickers, N.E. Bickers, N.E. Bickers, N.E. Bickers, P. Nozières, P.G.J. van Dongen, R. Bulla, R. Bulla, R.A. Weiner, R.A. Weiner, S. Kehrein, V. Janiš, V. Janiš, V.V. Sudakov, X.Y. Zhang, Y.M. Vilk   +34 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Difference inequality for stability of impulsive difference equations with distributed delays

Journal of Inequalities and Applications, 2011
In this paper, we consider a class of impulsive difference equations with distributed delays. By establishing an impulsive delay difference inequality and using the properties of "ρ-cone" and eigenspace of the spectral radius of non-negative ...
Long Shujun, Li Dingshi, Wang Xiaohu
doaj