Results 71 to 80 of about 341,746 (252)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Dynamical Behavior and Stability Analysis in a Stage-Structured Prey Predator Model with Discrete Delay and Distributed Delay

open access: yesAbstract and Applied Analysis, 2014
We propose a prey predator model with stage structure for prey. A discrete delay and a distributed delay for predator described by an integral with a strong delay kernel are also considered.
Chao Liu, Qingling Zhang
doaj   +1 more source

Robust Stability for Impulsive Systems With Polytope Uncertainties

open access: yesIEEE Access, 2019
This paper is concerned with robust stability for impulsive systems with polytope uncertainties. At first, the stability for impulsive systems without uncertainties is addressed by employing a Lyapunov-like functional.
Hanyong Shao, Wenjing Wang
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

On the Ulam-type stability of impulsive differential equations with multiple time delays

open access: yesArab Journal of Basic and Applied Sciences
In this article, we conduct a rigorous analysis of the Ulam-type stability of first-order impulsive delay differential equations (IP-D-D-Es) with multiple time-dependent delays.
Cemil Tunç, Osman Tunç
doaj   +1 more source

Iterative methods for solving Ambartsumian’s equations. Part 1

open access: yesИзвестия высших учебных заведений. Поволжский регион: Физико-математические науки, 2021
Background. Ambartsumian’s equation and its generalizations are one of the main integral equations of astrophysics, which have found wide application in many areas of physics and technology. An analytical solution to this equation is currently unknown,
I.V. Boykov, A.A. Shaldaeva
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

A simplified computer program for the prediction of the linear stability behavior of liquid propellant combustors [PDF]

open access: yes
A program for predicting the linear stability of liquid propellant rocket engines is presented. The underlying model assumptions and analytical steps necessary for understanding the program and its input and output are also given.
Eckert, K., Mitchell, C. E.
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

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