Results 61 to 70 of about 11,857 (246)
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Iterative methods for solving Ambartsumian’s equations. Part 1
Известия высших учебных заведений. Поволжский регион: Физико-математические науки, 2021 Background. Ambartsumian’s equation and its generalizations are one of the main integral equations of astrophysics, which have found wide application in many areas of physics and technology. An analytical solution to this equation is currently unknown,
I.V. Boykov, A.A. Shaldaeva
doaj +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Coupled memory sampled-data control for fractional stochastic wind energy conversion models
International Journal of Electrical Power & Energy SystemsThis study aims to design a coupled memory sampled-data control (CMSDC) for fractional stochastic wind energy conversion systems (WECSs). Theoretically, this paper introduces a permanent magnet synchronous generator (PMSG)-based WECS, which is crucial in
Girija Panneerselvam, Prakash Mani
doaj +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Scientific ReportsThe fixed point theory has been generalized mainly in two directions. One is the extension of the spaces, and the other is relaxing and generalizing the contractions. This paper aims to establish novel fixed point results of rational type generalized $$(\
Khaled Aldwoah +5 more
doaj +1 more source
Existence of positive solutions to a class of elastic beam equations
Journal of Hebei University of Science and Technology, 2017 Elastic beam is a kind of mathematical model in elastic mechanics and engineering physics. For now, this type of model is often used in real life. On the basis of the relative research on the elastic beam equations with one end fixed and one end sliding ...
Menglan JU, Wenxia WANG, Caiyun HAO
doaj +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source