Results 61 to 70 of about 83,271,276 (264)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Finite Difference Method for Solving Partial Integro-Differential Equations

open access: yesپژوهش‌های ریاضی, 2020
Introduction In this paper, we have introduced a new method for solving a class of the partial integro-differential equation with the singular kernel by using the finite difference method.
Majid Erfanian, Hamed Zeidabadi
doaj  

Analysis of some localized boundary-domain integral equations for transmission problems with variable coefficients [PDF]

open access: yes, 2011
This is the post-print version of the Article. The official published version can be found at the links below - Copyright @ 2011 Birkhäuser Boston.Some segregated systems of direct localized boundary-domain integral equations (LBDIEs) associated with ...
Mikhailov, SE   +4 more
core   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

On Coupled p-Laplacian Fractional Differential Equations with Nonlinear Boundary Conditions

open access: yesComplexity, 2017
This paper is related to the existence and uniqueness of solutions to a coupled system of fractional differential equations (FDEs) with nonlinear p-Laplacian operator by using fractional integral boundary conditions with nonlinear term and also to ...
Aziz Khan   +3 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Coupled implicit fractional integro-differential systems with mixed operators in weighted spaces

open access: yesBoundary Value Problems
This paper investigates a class of coupled nonlinear implicit fractional integro-differential systems featuring Riemann–Liouville derivatives of distinct orders and nonlocal boundary conditions.
Abdulrahman A. Sharif   +2 more
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

APPLICATION OF THE CONTINUOUS OPERATOR METHOD TO THE SOLUTION OF THE POCKLINGTON AND GALLEN EQUATIONS FOR THIN WIRE ANTENNAS

open access: yesИзвестия высших учебных заведений. Поволжский регион: Физико-математические науки, 2020
Background. One of the central tasks in microwave electronics is the construction of miniature antennas with high performance. The main equations used in modeling wire antennas of various configurations are the Pocklington, Gallen equations, singular ...
I. V. Boykov, P. V. Aykashev
doaj   +1 more source

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