Results 81 to 90 of about 341,444 (262)

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

On the Ulam-type stability of impulsive differential equations with multiple time delays

open access: yesArab Journal of Basic and Applied Sciences
In this article, we conduct a rigorous analysis of the Ulam-type stability of first-order impulsive delay differential equations (IP-D-D-Es) with multiple time-dependent delays.
Cemil Tunç, Osman Tunç
doaj   +1 more source

Robust Stability for Impulsive Systems With Polytope Uncertainties

open access: yesIEEE Access, 2019
This paper is concerned with robust stability for impulsive systems with polytope uncertainties. At first, the stability for impulsive systems without uncertainties is addressed by employing a Lyapunov-like functional.
Hanyong Shao, Wenjing Wang
doaj   +1 more source

Iterative methods for solving Ambartsumian’s equations. Part 1

open access: yesИзвестия высших учебных заведений. Поволжский регион: Физико-математические науки, 2021
Background. Ambartsumian’s equation and its generalizations are one of the main integral equations of astrophysics, which have found wide application in many areas of physics and technology. An analytical solution to this equation is currently unknown,
I.V. Boykov, A.A. Shaldaeva
doaj   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Existence of positive solutions to a class of elastic beam equations

open access: yesJournal of Hebei University of Science and Technology, 2017
Elastic beam is a kind of mathematical model in elastic mechanics and engineering physics. For now, this type of model is often used in real life. On the basis of the relative research on the elastic beam equations with one end fixed and one end sliding ...
Menglan JU, Wenxia WANG, Caiyun HAO
doaj   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin   +12 more
wiley   +1 more source

Coupled memory sampled-data control for fractional stochastic wind energy conversion models

open access: yesInternational Journal of Electrical Power & Energy Systems
This study aims to design a coupled memory sampled-data control (CMSDC) for fractional stochastic wind energy conversion systems (WECSs). Theoretically, this paper introduces a permanent magnet synchronous generator (PMSG)-based WECS, which is crucial in
Girija Panneerselvam, Prakash Mani
doaj   +1 more source

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