Results 71 to 80 of about 1,911,708 (347)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
K-stability Implies CM-stability [PDF]
, 2017 In this paper, we prove that any polarized K-stable manifold is CM-stable. This extends what I did for Fano manifolds in my 2012 paper.
openaire +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Uncertainty factor in modeling dynamics of economic systems [PDF]
Компьютерные исследования и моделирование, 2018 Analysis and practical aspects of implementing developed in the control theory robust control methods in studying economic systems is carried out. The main emphasis is placed on studying results obtained for dynamical systems with structured uncertainty.
Leonid E. Varshavsky
doaj +1 more source
Use of Recycled Crushed Concrete (RCC) Fines for Potential Soil Stabilization [PDF]
, 2016 This study evaluated the use of Recycled Crushed Concrete (RCC) Fines for potential soil stabilization. Soil stabilization is the enhancement of subgrade stability to improve the constructability of successive pavement layers.
Brandon, Varilek +4 more
core +1 more source
Stabilized high-power laser system for the gravitational wave detector advanced LIGO [PDF]
, 2012 An ultra-stable, high-power cw Nd:YAG laser system, developed for the ground-based gravitational wave detector Advanced LIGO (Laser Interferometer Gravitational-Wave Observatory), was comprehensively characterized.
Bogan, C. +12 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Pharmacokinetic study of a new 4,5-dihydroisoxazole-5-carboxamide derivative in rats
Разработка и регистрация лекарственных средствIntroduction. 3-(2-butyl-5-chloro-1H-imidazole-4-yl)-N-[4-methoxy-3-(trifluoromethyl)phenyl]-4,5-dihydro-1,2-oxazole-5-carboxamide (R004) is a prospective new molecule for the treatment of rheumatoid arthritis.
I. I. Yaichkov +6 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Ensuring the growth of the country’s economy
Путеводитель предпринимателяThe article examines and analyzes the problems and issues of the dynamics of the country’s economy (GDP) under the influence of external and internal factors and conditions in the second half of the year and in general for 2023. The dynamics of inflation
L. A. Akhmetov, M. A. Bulavina
doaj +1 more source