Results 51 to 60 of about 46,630 (268)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Feedback Stabilization of Quasi-One-Sided Lipschitz Nonlinear Discrete-Time Systems with Reduced-Order Observer

Mathematics
The feedback stabilization problem for nonlinear discrete-time systems with a reduced-order observer is investigated, in which the nonlinear terms of the systems satisfy the quasi-one-sided Lipschitz condition.
Yanbin Zhao, Wenqiang Dong
doaj   +1 more source

Analysis and Design of Robust Positivity and Stability for Continuous-Time Linear Uncertain Systems

Journal of Applied Mathematics, 2015
This paper deals with the analysis and design of positivity and stability of linear continuous conic systems. First, two robustness analysis theorems are proposed for the systems with state-feedback.
Kuo-Liang Yen, Kuo-Shong Wang, Yau-Tarng Juang   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Asymptotic Stabilization of Delayed Linear Fractional-Order Systems Subject to State and Control Constraints

Fractal and Fractional, 2022
Studies have shown that fractional calculus can describe and characterize a practical system satisfactorily. Therefore, the stabilization of fractional-order systems is of great significance.
Xindong Si, Zhen Wang, Zhibao Song, Ziye Zhang   +3 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Robust stabilization of hybrid uncertain stochastic systems with time-varying delay by discrete-time feedback control

Advances in Difference Equations, 2017
This paper is concerned with the robust stabilization problem for a class of continuous-time hybrid uncertain stochastic systems with time-varying delay.
Yuyuan Li, Chunhai Kou
doaj   +1 more source

Finite-Time Simultaneous Stabilization for Stochastic Port-Controlled Hamiltonian Systems over Delayed and Fading Channels

Complexity, 2020
In this paper, a finite-time simultaneous stabilization problem is investigated for a set of stochastic port-controlled Hamiltonian (PCH) systems over delayed and fading noisy channels. The feedback control signals transmitted via a communication network
Yaping Tang, Weiwei Sun, Dongqing Liu
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A new switching strategy for exponential stabilization of uncertain discrete-time switched linear systems in guaranteed cost control problem

Iranian Journal of Electrical and Electronic Engineering, 2015
Uncertain switched linear systems are known as an important class of control systems. Performance of these systems is affected by uncertainties and its stabilization is a main concern of recent studies.
M. R. Ramezani-al, A. Vahidian Kamyad, N. Pariz   +2 more
doaj