Results 111 to 120 of about 69,372 (313)

Foreign policy change in Brazil: comparing Castelo Branco (1964-1967) and Fernando Collor (1990-1992) [PDF]

Brazilian Political Science Review, 2013
In this article, I intended to develop an analytical schema to analyze moments of redirection in Brazilian Foreign Policy. The schema encompasses the following logic: sources from national and international contexts may influence the domestic political ...
Ítalo Beltrão Sposito
doaj  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Power System Stability Enhancement by Single Network Adaptive Critic Stabilizers

, 2009
This paper proposes a Single Network Adaptive Critic (SNAC) based Power System Stabilizer (PSS) for enhancing the small-signal stability of power systems over a wide range of operating conditions.
Gurrala, Gurunath, Sen, Indraneel, Padhi, Radhakant   +2 more
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Stabilization of γ-sterilized biomedical polyolefins by synergistic mixtures of oligomeric stabilizers. Part II. Polypropylene matrix

, 2007
In our previous study we have found the synergistic combinations of stabilizers which follow different mechanisms of stabilization and are approved for food contact and biomedical applications.
Alariqi, Sameh A.S., Kumar, A. Pratheep, Alariqi, Sameh A. S., Rao, B.S.M. Rao, Singh, R. P., Rao, B. S. M., Singh, R.P.   +6 more
core   +1 more source

Cast composite solid propellants with different combustion stabilizers [PDF]

Scientific Technical Review, 2015
The effect of four different compounds as the combustion stabilizers of composite solid propellants based on the AP/HTPB/IPDI has been presented in this paper.
Rodić Vesna, Dimić Mirjana, Brzić Saša, Gligorijević Nikola   +3 more
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Rozdíly v aktivaci vybraných svalů u lyžařů s jednostrannou nadkolenní amputací při jízdě na lyžích [PDF]

ACC Journal, 2011
V příspěvku se zabýváme porovnáváním jednotlivých případových studií analýzy specifické lokomoce lyžování – lyžařů s jednostrannou nadkolenní amputací (skupina LW2).
Petra Matošková, Vladimír Süss, Bronislav Kračmar, Milan Bílý   +3 more
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source