Results 1 to 10 of about 3,398 (136)

Pyroxasulfone and Isoproturon Nanosuspensions for Sustainable Wheat Production: Efficacy, Safety, and Yield Benefits [PDF]

Plants
Wheat production, vital for global food security, faces significant threats from weed competition. Conventional herbicide formulation with high application dosage raises environmental concerns, driving the need for efficient, low-dosage delivery systems ...
Xiaolin Wang, Xiaomeng Guo, Xuebiao Zhang, Chao Xu, Dongsheng Li, Kebing Yao, Xuejian Cheng, Kang Miao   +7 more
doaj   +2 more sources

Preparation, characterization and in vitro evaluation of atorvastatin nanosuspensions. [PDF]

PLoS ONE
Poorly water-soluble drugs present a significant challenge for pharmaceutical development, particularly affecting the pharmacokinetics of orally administered drugs due to their poor dissolution.
Yaman Ahmad Akour, Ahmad Aljaberi, Saja H Hamed, Alaa Altaher, Eman M Migdadi   +4 more
doaj   +2 more sources

Preparation and Comprehensive Evaluation of the Efficacy and Safety of Chlorantraniliprole Nanosuspension

Toxics
Chlorantraniliprole is a broad-spectrum insecticide that has been widely used to control pests in rice fields. Limited by its low solubility in both water and organic solvents, the development of highly efficient and environmentally friendly ...
Haixin Cui, Zhanghua Zeng
exaly   +3 more sources

A recent solidification approach for nanosuspension: formulation, optimisation and evaluation of canagliflozin immediate release pellets [PDF]

Folia Medica, 2022
Introduction: Canagliflozin is a BCS class IV drug. Nanosuspension is known to enhance the saturation solubility and dissolution rate of poorly soluble drugs owing to the increased surface area of nanosized particles. Aim: In the present
Nisha C. Patel, Hitesh A. Patel
doaj   +3 more sources

Enhancing pharmaceutical potential and oral bioavailability of Allium cepa nanosuspension in male albino rats using response surface methodology

Asian Pacific Journal of Tropical Biomedicine, 2022
Objective: To enhance the pharmaceutical potential and oral bioavailability of quercetin contents of Allium cepa peel extract by novel nanosuspension technology.
Fatiqa Zafar, Nazish Jahan, Shaukat Ali, Saba Jamil, Riaz Hussain, Saba Aslam   +5 more
doaj   +1 more source

Development of Nanosuspension of Artemisia absinthium Extract as Novel Drug Delivery System to Enhance Its Bioavailability and Hepatoprotective Potential

Journal of Functional Biomaterials, 2023
A nanosuspension of Artemisia absinthium extract was formulated and characterized for the enhancement of bioavailability and better hepatoprotective efficacy. The nanosuspension of A.
Nazish Jahan, Fareeha Kousar, Khalil Ur Rahman, Syeeda Iram Touqeer, Naseem Abbas   +4 more
doaj   +1 more source

DEVELOPMENT AND OPTIMIZATION OF ALBENDAZOLE NANOSUSPENSION AS LOCAL ADJUVANT THERAPY FOR TREATMENT OF ENTEROBIASIS [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 2020
The aim was to develop an optimized albendazole (ALB) nanosuspension to improve its solubility and therapeutic activity as an adjuvant localized therapy for treatment of the pinworm infection to enhance oral treatment outcomes using Box–Behnken design ...
Ayat Allam, Mahmoud EL-Badry, Gihan Fetih, Aml Mekkawy   +3 more
doaj   +1 more source

Nanosuspension enhances dissolution rate and oral bioavailability of Terminalia arjuna bark extract in vivo and in vitro

Asian Pacific Journal of Tropical Biomedicine, 2020
Objective: To enhance the dissolution rate and oral bioavailability of Terminalia arjuna bark extract by formulating its nanosuspension. Methods: Nanoprecipitation approach was used for the formulation of nanosuspension using polysorbate-80 as a ...
Fatiqa Zafar, Nazish Jahan, Khalil-Ur-Rahman, Muhammad Rafique Asi, Waseeq-Ul-Islam Zafar   +4 more
doaj   +1 more source

Investigation of pre-clinical pharmacokinetic parameters of atovaquone nanosuspension prepared using a pH-based precipitation method and its pharmacodynamic properties in a novel artemisinin combination

Journal of Global Antimicrobial Resistance, 2020
Objectives: Recently, a growing resistance to antimalarial drugs such as chloroquine, sulfadoxine–pyrimethamine, artemisinin derivatives and mefloquine has been observed. The pharmacokinetic limitation of the current therapy and multi-drug resistance has
Harsha Kathpalia, Siddhesh Juvekar, Krishnapriya Mohanraj, Mrunal Apsingekar, Supriya Shidhaye   +4 more
doaj   +1 more source

Design and Development of Chitosan Based Etravirine Nanosuspension [PDF]

Nanomedicine Research Journal, 2022
Objective(s): The objective of this study was to design, develop, optimize, and evaluate Chitosan based Etravirine Nanosuspension to enhance their solubility and extent of release.Methods: The Chitosan based Etravirine Nanosuspension was formulated by ...
Sathesh Kumar Sukumaran, C. Venkatasubramaniyan   +1 more
doaj   +1 more source