Results 11 to 20 of about 4,453 (214)

Preparation, characterization and pharmacokinetics of cyadox nanosuspension [PDF]

open access: yesScientific Reports, 2017
An increase in number of newly developed synthetic drugs displays bioavailability constraints because of poor water solubility. Nanosuspensions formulation may help to overwhelm these problems by increasing dissolution velocity and saturation solubility.
Adeel Sattar   +8 more
doaj   +4 more sources

Nanosuspension: An approach to enhance solubility of drugs

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2011
One of the major problems associated with poorly soluble drugs is very low bioavailability. The problem is even more complex for drugs like itraconazole, simvastatin, and carbamazepine which are poorly soluble in both aqueous and nonaqueous media ...
Vishal R Patel, Y K Agrawal
doaj   +4 more sources

NANOSUSPENSION: AN OVERVIEW

open access: yesInternational Journal of Current Pharmaceutical Research, 2017
Nanosuspensions are important carriers to develop novel drug formulations. Nanosuspensions have emerged as a promising strategy for the efficient delivery of hydrophobic drugs because of their versatile features and unique advantages. Nanosuspension technology solved the problem of drugs which are poorly aqueous soluble and less bioavailability ...
Smita S. Aher   +2 more
core   +5 more sources

NANOSUSPENSION TECHNOLOGY: A REVIEW

open access: yes, 2021
Solubility is the crucial factor for drug effectiveness, independence of the route of administration. Large proportions of newly discovered drugs are water insoluble, and therefore poorly bioavailable contributing to deserted development effort. These so‐called 'Brickellia' candidates can now be delivered by formulating them into Nanosuspension ...
T. Pavani Priya, K. Manasa, Ch. Greeshmika1, B. Hemalatha, K. Padmalatha
openaire   +3 more sources

NANOSUSPENSION: AN OVERVIEW

open access: yesJournal of Drug Delivery and Therapeutics, 2013
Nanotechnology has emerged as a tremendous field in the medicine. Nano refers to particles size range of 1-1000nm. Nanosuspensions are part of nanotechnology. Nanosuspensions contain submicron colloidal dispersion of pharmaceutical active ingredient particles in a liquid phase stabilized by surfactants.
Akanksha Chandra   +3 more
openaire   +2 more sources

An Overview of Recent Patents on Nanosuspension

open access: yesRecent Patents on Drug Delivery & Formulation, 2014
Pharmaceutical scientists involved in drug discovery and drug development are facing serious problems with newer poorly water soluble drugs with respect to their dissolution and bioavailability. Reducing the particle size of active pharmaceutical ingredient has been an efficient and reliable method for improving the bioavailability of insoluble drugs ...
Modh, Nirav   +4 more
openaire   +5 more sources

ANTIBIOTICS NANOSUSPENSION: A REVIEW

open access: yesJournal of Drug Delivery and Therapeutics, 2017
Nanosuspensions are colloidal dispersions and biphasic system consisting of drug particles dispersed in an aqueous vehicle in which the diameter of the suspended particle is less than 1μm in size. Many drugs including antibiotics are having poor solubility. Nanosuspensions have proven to be a better alternative over other approaches currently available
Merin Mathew   +3 more
openaire   +4 more sources

Effects of oridonin nanosuspension on cell proliferation and apoptosis of human prostatic carcinoma PC-3 cell line

open access: yesInternational Journal of Nanomedicine, 2010
Zhen Zhang, Xiumei Zhang, Wei Xue, Yuna YangYang, Derong Xu, Yunxue Zhao, Haiyan LouSchool of Medicine, Shandong University, Jinan, Republic of ChinaAbstract: This study aims to investigate the inhibitory effects of oridonin nanosuspension on human ...
Zhen Zhang, Xiumei Zhang, Wei Xue, et al
doaj   +3 more sources

Anionic Surfactant Based Topical Curcumin Nanosuspension: Fabrication, Characterization and Evaluation

open access: yesNano Biomedicine and Engineering, 2013
Curcumin, a hydrophobic polyphenol isolated from dried rhizomes of turmeric exhibits diverse pharmacological activities including anti-bacterial. However, the clinical usefulness of curcumin was limited mainly due to low aqueous solubility and stability.
Moorthi Chidambaram   +3 more
doaj   +2 more sources

Antibacterial activity of guava (Psidium guajava L.) leaf ethanolic extract nanosuspension against Escherichia coli bacteria [PDF]

open access: yesPharmaciana
Diarrhea is a condition where a person has bowel movements three or more times a day, with consistent stools. One of the common bacteria that causes diarrhea is Escherichia coli.
Lusi Nurdianti   +5 more
doaj   +2 more sources

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