Results 11 to 20 of about 4,959 (213)

NANOSUSPENSION: AN OVERVIEW [PDF]

open access: yesInternational Journal of Current Pharmaceutical Research, 2017
Nanosuspensions are important carriers to develop novel drug formulations. Nanosuspensions have emerged as a promising strategy for the efficient delivery of hydrophobic drugs because of their versatile features and unique advantages. Nanosuspension technology solved the problem of drugs which are poorly aqueous soluble and less bioavailability ...
Smita S. Aher   +2 more
core   +5 more sources

ANTIBIOTICS NANOSUSPENSION: A REVIEW [PDF]

open access: yesJournal of Drug Delivery and Therapeutics, 2017
Nanosuspensions are colloidal dispersions and biphasic system consisting of drug particles dispersed in an aqueous vehicle in which the diameter of the suspended particle is less than 1μm in size. Many drugs including antibiotics are having poor solubility. Nanosuspensions have proven to be a better alternative over other approaches currently available
Merin Mathew   +3 more
openaire   +3 more sources

NANOSUSPENSION: AN OVERVIEW

open access: yesJournal of Drug Delivery and Therapeutics, 2013
Nanotechnology has emerged as a tremendous field in the medicine. Nano refers to particles size range of 1-1000nm. Nanosuspensions are part of nanotechnology. Nanosuspensions contain submicron colloidal dispersion of pharmaceutical active ingredient particles in a liquid phase stabilized by surfactants.
Akanksha Chandra   +3 more
openaire   +2 more sources

Nanosuspension: An approach to enhance solubility of drugs

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2011
One of the major problems associated with poorly soluble drugs is very low bioavailability. The problem is even more complex for drugs like itraconazole, simvastatin, and carbamazepine which are poorly soluble in both aqueous and nonaqueous media ...
Vishal R Patel, Y K Agrawal
doaj   +2 more sources

Preparation, characterization and pharmacokinetics of cyadox nanosuspension

open access: yesScientific Reports, 2017
An increase in number of newly developed synthetic drugs displays bioavailability constraints because of poor water solubility. Nanosuspensions formulation may help to overwhelm these problems by increasing dissolution velocity and saturation solubility.
Adeel Sattar   +8 more
doaj   +2 more sources

An Overview of Recent Patents on Nanosuspension

open access: yesRecent Patents on Drug Delivery & Formulation, 2014
Pharmaceutical scientists involved in drug discovery and drug development are facing serious problems with newer poorly water soluble drugs with respect to their dissolution and bioavailability. Reducing the particle size of active pharmaceutical ingredient has been an efficient and reliable method for improving the bioavailability of insoluble drugs ...
Modh, Nirav   +4 more
openaire   +5 more sources

NANOSUSPENSION TECHNOLOGY: A REVIEW

open access: yes, 2021
Solubility is the crucial factor for drug effectiveness, independence of the route of administration. Large proportions of newly discovered drugs are water insoluble, and therefore poorly bioavailable contributing to deserted development effort. These so‐called 'Brickellia' candidates can now be delivered by formulating them into Nanosuspension ...
T. Pavani Priya, K. Manasa, Ch. Greeshmika1, B. Hemalatha, K. Padmalatha
openaire   +3 more sources

Effects of oridonin nanosuspension on cell proliferation and apoptosis of human prostatic carcinoma PC-3 cell line [PDF]

open access: yesInternational Journal of Nanomedicine, 2010
Zhen Zhang, Xiumei Zhang, Wei Xue, Yuna YangYang, Derong Xu, Yunxue Zhao, Haiyan LouSchool of Medicine, Shandong University, Jinan, Republic of ChinaAbstract: This study aims to investigate the inhibitory effects of oridonin nanosuspension on human ...
Zhen Zhang, Xiumei Zhang, Wei Xue, et al
doaj   +2 more sources

Transformation of eutectic emulsion to nanosuspension fabricating with solvent evaporation and ultrasonication technique

open access: yesInternational Journal of Nanomedicine, 2016
Thawatchai Phaechamud,1 Sarun Tuntarawongsa2 1Department of Pharmaceutical Technology, 2Pharmaceutical Intelligence Unit Prachote Plengwittaya, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, Thailand Abstract: Eutectic solvent can solubilize
Phaechamud T, Tuntarawongsa S
doaj   +1 more source

Enhancement of oral bioavailability of quercetin by metabolic inhibitory nanosuspensions compared to conventional nanosuspensions [PDF]

open access: yesDrug Delivery, 2021
Quercetin-loaded nanosuspensions (Que-NSps) added metabolic inhibitors were evaluated as drug delivery system to promote the oral bioavailability of quercetin. Que-NSps were prepared respectively using d-alpha tocopherol acid polyethylene glycol succinate (TPGS) or Soybean Lecithin (SPC) as stabilizer. On the basis, Piperine (Pip) or sodium oleate (SO)
Haowen Li   +5 more
openaire   +3 more sources

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