Results 21 to 30 of about 4,959 (213)

Nanotechnology Approach for Exploring the Enhanced Bioactivities and Biochemical Characterization of Freshly Prepared Nigella sativa L. Nanosuspensions and Their Phytochemical Profile

Frontiers in Bioengineering and Biotechnology, 2022
Nigella sativa is one of the most commonly used medicinal plants as it exhibits several pharmacological activities such as antioxidant, antibacterial, anticancer, antidiabetic, and hemolytic.
Tayyab Ali, Fatma Hussain, Muhammad Naeem, Ajmal Khan, Ahmed Al-Harrasi   +4 more
doaj   +1 more source

Development of Polymer and Surfactant Based Naringenin Nanosuspension for Improvement of Stability, Antioxidant, and Antitumour Activity

Journal of Chemistry, 2020
Nanosuspensions are widely reported to enhance the solubility of poorly soluble drugs. In addition to enhancement in solubility, improvement of stability and therapeutic efficacy would be an added advantage.
Shadab Md, Nabil A. Alhakamy, Sohail Akhter, Zuhier A. Y. Awan, Hibah M. Aldawsari, Waleed S. Alharbi, Anzarul Haque, Hira Choudhury, Ponnurengam Malliappan Sivakumar   +8 more
doaj   +1 more source

Formulation and Evaluation of Ketoconazole Nano-suspension

Journal of Food and Pharmaceutical Sciences, 2023
The use of antifungals that are widely used by the public is ketoconazole. Ketoconazole is included in the Biopharmaceutical Classification System (BCS) II category, where the drug is poorly soluble in water but has high permeability.
Eriska Agustin, Gita Deslia Sari
doaj   +1 more source

Fluconazole Nanosuspension Enhances In Vitro Antifungal Activity against Resistant Strains of Candida albicans [PDF]

Pharmaceutical Sciences, 2022
Background: Recently, nanoparticles were widely used in drug delivery. Fluconazole (FLZ) is a lipid-soluble antifungal, which is utilized in treating fungal infections.
Katayoun Morteza-Semnani, Majid Saeedi, Jafar Akbari, Maryam Moazeni, Houman Seraj, Elham Daftarifard, Mahgol Tajbakhsh, Seyyed Mohammad Hassan Hashemi, Amirhossein Babaei   +8 more
doaj   +1 more source

FORMULATION AND EVALUATION OF NANOSUSPENSION OF VALSARTAN [PDF]

, 2018
Objective: The objective of the present research work was to formulate and evaluate Valsartan nanosuspension by nanoprecipitation ultra sonication method using different polymers to enhance solubility and bioavailability of the poorly water-soluble drug ...
Shikha Agrawal, Amreen Khan, Agrawal, Shikha, Manishaanjane ., Khan, Amreen, Manishaanjane   +5 more
core   +2 more sources

Improved dissolution and oral absorption by co-grinding active drug probucol and ternary stabilizers mixtures with planetary beads-milling method

Asian Journal of Pharmaceutical Sciences, 2019
The objective of this work is to construct a nanosuspension drug delivery system of probucol, a BCS II drug, in order to improve its dissolution and oral bioavailability.
Fang Li, Linsen Li, Shaoning Wang, Yan Yang, Jia Li, Dongchun Liu, Sijie Zhang, Siling Wang, Hui Xu   +8 more
doaj   +1 more source

Solubility Determination of c-Met Inhibitor in Solvent Mixtures and Mathematical Modeling to Develop Nanosuspension Formulation

Molecules, 2021
The solubility and dissolution thermodynamics of new c-Met inhibitor, ABN401, were determined in eleven solvents and Transcutol® HP–water mixture (TWM) from 298.15 to 318.15 K.
Maharjan Ravi, Tripathi Julu, Nam Ah Kim, Kyeung Eui Park, Seong Hoon Jeong   +4 more
doaj   +1 more source

Formulation and Process Optimization of Rauvolfia serpentina Nanosuspension by HPMC and In Vitro Evaluation of ACE Inhibitory Potential

Journal of Functional Biomaterials, 2022
Angiotensin converting enzyme (ACE) overactivation is one of the primary causes of hypertension, which leads to cardiovascular disorders all over the world.
Syeeda Iram Touqeer, Nazish Jahan, Naseem Abbas, Ahsan Ali   +3 more
doaj   +1 more source

Sustained-release progesterone nanosuspension following intramuscular injection in ovariectomized rats [PDF]

, 2010
Heba F SalemFaculty of Pharmacy, Beni-Suef University, Beni-Suef, EgyptAbstract: The production of an intramuscular (IM) injection of natural progesterone would provide a safer solution than using semi synthetic progesterone.
null Salem, Heba F Salem
core   +1 more source

Enhanced ex vivo intestinal absorption of olmesartan medoxomil nanosuspension: Preparation by combinative technology

Saudi Pharmaceutical Journal, 2016
The purpose of this study was to develop nanosuspension based on combinative technology to enhance the intestinal absorption of Olmesartan medoxomil (OLM), a potent antihypertensive agent with limited oral bioavailability. Two combinative approaches were
Zenab Attari, Amita Bhandari, P.C. Jagadish, Shaila Lewis   +3 more
doaj   +1 more source