Results 21 to 30 of about 4,453 (214)
International Journal of Nanomedicine, 2016 Thawatchai Phaechamud,1 Sarun Tuntarawongsa2 1Department of Pharmaceutical Technology, 2Pharmaceutical Intelligence Unit Prachote Plengwittaya, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, Thailand Abstract: Eutectic solvent can solubilize
Phaechamud T, Tuntarawongsa S
doaj +1 more source
Preparation and Characterization of Nanosuspension of Aprepitant by H96 Process [PDF]
Advanced Pharmaceutical Bulletin, 2016 Purpose: Nanosuspension in drug delivery is known to improve solubility, dissolution and eventually bioavailability of the drugs. The purpose of the study was to compare particle size of nanosuspensions prepared by the first generation approach and H96 ...
Sunethra Kalvakuntla +3 more
doaj +2 more sources
Ziprasidone Hydrochloride Nanosuspension for Bioavailability Enhancement: Design, Development and Evaluation [PDF]
E3S Web of ConferencesZiprasidone hydrochloride belongs to BCS Class II since it possesses high membrane permeability along with low solubility properties. Research shows that the full available amount of a 20 mg dose reaches the body system at a rate of 60%.A research study ...
Paun Jalpa S. +3 more
doaj +2 more sources
Enhancement of oral bioavailability of quercetin by metabolic inhibitory nanosuspensions compared to conventional nanosuspensions [PDF]
Drug Delivery, 2021 Quercetin-loaded nanosuspensions (Que-NSps) added metabolic inhibitors were evaluated as drug delivery system to promote the oral bioavailability of quercetin. Que-NSps were prepared respectively using d-alpha tocopherol acid polyethylene glycol succinate (TPGS) or Soybean Lecithin (SPC) as stabilizer. On the basis, Piperine (Pip) or sodium oleate (SO)
Haowen Li +5 more
openaire +3 more sources
Formulation and Evaluation of Ketoconazole Nano-suspension
Journal of Food and Pharmaceutical Sciences, 2023 The use of antifungals that are widely used by the public is ketoconazole. Ketoconazole is included in the Biopharmaceutical Classification System (BCS) II category, where the drug is poorly soluble in water but has high permeability.
Eriska Agustin, Gita Deslia Sari
doaj +1 more source
Asian Journal of Pharmaceutical Sciences, 2019 The objective of this work is to construct a nanosuspension drug delivery system of probucol, a BCS II drug, in order to improve its dissolution and oral bioavailability.
Fang Li +8 more
doaj +1 more source
Molecules, 2021 The solubility and dissolution thermodynamics of new c-Met inhibitor, ABN401, were determined in eleven solvents and Transcutol® HP–water mixture (TWM) from 298.15 to 318.15 K.
Maharjan Ravi +4 more
doaj +1 more source
Journal of Functional Biomaterials, 2022 Angiotensin converting enzyme (ACE) overactivation is one of the primary causes of hypertension, which leads to cardiovascular disorders all over the world.
Syeeda Iram Touqeer +3 more
doaj +1 more source
Saudi Pharmaceutical Journal, 2016 The purpose of this study was to develop nanosuspension based on combinative technology to enhance the intestinal absorption of Olmesartan medoxomil (OLM), a potent antihypertensive agent with limited oral bioavailability. Two combinative approaches were
Zenab Attari +3 more
doaj +1 more source
Interactions between nanoparticles in nanosuspension [PDF]
Advances in Colloid and Interface Science, 2019 Nanoparticles are particles with a characteristic dimension below 100 nm. The properties of nanoparticles differ substantially from those of "big" colloidal particles (size bigger than 1 μm) because radius of surface forces, which is around 100 nm, is greater than or comparable with the nanoparticles size.
N M, Kovalchuk +4 more
openaire +4 more sources