Results 101 to 110 of about 97,749 (304)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Two stable steady states in the Hodgkin-Huxley axons [PDF]

open access: yes, 1983
Two stable steady states were found in the numerical solution of the Hodgkin-Huxley equations for the intact squid axon bathed in potassium-rich sea water with an externally applied inward current. Under the conditions the two stable steady-states exist,
Aihara, K., Matsumoto, G.
core   +1 more source

Self-healing strategy for distribution networks with AC flexible interconnection devices

open access: yesFrontiers in Energy Research
The closing-loop and splitting-loop operations of sectionalizing switches and tie switches serve as crucial means for self-healing in distribution network feeder areas.
Xiaojun Ni   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Control of a Four-Port DC–DC Converter for Photovoltaic Systems Integrating Batteries and Supercapacitors

open access: yesIEEE Access
The integration of batteries and supercapacitors into a photovoltaic (PV) system using a multiport dc-dc converter offers an attractive alternative to conventional configurations with multiple two-port dc–dc converters.
Diego Rojas   +4 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

A Chimeric NaV1.8 Channel Expression System Based on HEK293T Cell Line

open access: yesFrontiers in Pharmacology, 2018
Among the nine voltage-gated sodium channel (NaV) subtypes, NaV1.8 is an attractive therapeutic target for pain. The heterologous expression of recombinant NaV1.8 currents is of particular importance for its electrophysiological and pharmacological ...
Xi Zhou   +6 more
doaj   +1 more source

On stable currents in positively pinched curved hypersurfaces [PDF]

open access: yesColloquium Mathematicum, 2003
Summary: Let \(M^n\) \((n\geq 3)\) be an \(n\)-dimensional complete bypersurface in a real space form \(N(c)\) \((c\geq 0)\). We prove that if the sectional curvature \(K_M\) of \(M\) satisfies the following pinching condition: \(c+\delta< K_M\leq c+1\), where \(\delta=\tfrac 15\) for \(n\geq 4\) and \(\delta =\frac 14\) for \(n=3\), then there are no ...
openaire   +2 more sources

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