Results 81 to 90 of about 2,107,862 (301)
Stable angina: current guidelines and advances in management [PDF]
Prescriber, 2013 Abstract Our Drug Review discusses the current recommended management of stable angina, focussing on secondary prevention and the control of symptoms, followed by sources of further information and an analysis of prescription data.
Anoop Shah, Keith Fox
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Laboratory modelling of the effects of temporal changes of estuarine-fresh-water discharge rates on the propagation speed of oceanographic coastal currents [PDF]
, 2010 In this paper, results of laboratory experiments simulating buoyancy-driven coastal currents produced by estuarine discharges into the ocean, are discussed.
PETER J. THOMAS +3 more
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FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
LONG-TERM OBSERVATIONS OF CURRENTS IN TANABE BAY
, 1983 A series of long-term observations of currents has been carried out at the Tower Station, Shirahama Oceanographic Observatory to find dynamical behaviour of coastal water in TanabeBay.
海象(流れ)観測グループ
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Stable ischemic heart disease in women: current perspectives
International Journal of Women's Health, 2017 Cardiovascular disease is the leading cause of death in women accounting for 1 in every 4 female deaths. Pathophysiology of ischemic heart disease in women includes epicardial coronary artery, endothelial dysfunction, coronary vasospasm, plaque erosion and spontaneous coronary artery dissection. Angina is the most common presentation of stable ischemic
Samad, Fatima +2 more
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Two applications of the Theory of Currents [PDF]
, 2013 In the first part of the thesis we find an adapted version of the Rademacher theorem of differentiability of Lipschitz functions, when the Lebesgue measure on the euclidean space is replaced by a generical Radon measure.
MARCHESE, ANDREA
core
Classification of stable currents in the product of spheres
Tamkang Journal of Mathematics, 2011 No ...
openaire +2 more sources