Results 111 to 120 of about 2,107,862 (301)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Control of a Four-Port DC–DC Converter for Photovoltaic Systems Integrating Batteries and Supercapacitors

IEEE Access
The integration of batteries and supercapacitors into a photovoltaic (PV) system using a multiport dc-dc converter offers an attractive alternative to conventional configurations with multiple two-port dc–dc converters.
Diego Rojas, Javier Munoz, Duberney Murillo-Yarce, Marco Rivera, Patrick Wheeler   +4 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Surf zone currents and influence on surfability [PDF]

, 2003
Surfing headlands are shallow and exposed coastal features that provide a specific form of breaking wave allowing a board-rider to ride on the unbroken wave face.
Black, Kerry P., Phillips, David, Mead, Shaw T., Healy, Terry R.   +3 more
core  

A Chimeric NaV1.8 Channel Expression System Based on HEK293T Cell Line

Frontiers in Pharmacology, 2018
Among the nine voltage-gated sodium channel (NaV) subtypes, NaV1.8 is an attractive therapeutic target for pain. The heterologous expression of recombinant NaV1.8 currents is of particular importance for its electrophysiological and pharmacological ...
Xi Zhou, Yunxiao Zhang, Dongfang Tang, Songping Liang, Ping Chen, Cheng Tang, Zhonghua Liu   +6 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Field-aligned currents and ionospheric parameters deduced from EISCAT radar measurements in the post-midnight sector [PDF]

, 2002
International audienceAttempting to derive the field-aligned current (FAC) density using the EISCAT radar and to understand the role of the ionosphere on closing FACs, we conducted special radar experiments with the EISCAT radar on 9 October 1999.
Nagatsuma, T., Gjerloev, J. W., S. Nozawa, T. Nagatsuma, M. Sugino, S. C. Buchert, Nozawa, S., Fujii, R., Buchert, S. C., Kosch, M. J., M. J. Kosch, Sugino, M., R. Fujii, J. W. Gjerloev   +13 more
core   +2 more sources

On the nonexistence of stable currents in submanifolds of a Euclidean space [PDF]

Tohoku Mathematical Journal, 2004
Let \(M^m\) be a compact Riemannian manifold immersed in Euclidean space \(\mathbb R^{m+k}\). The main result of the paper is that there are no stable currents in \(M^m\) if one of the following pinching conditions holds: 1) The sectional curvature \(K\) satisfies \(K > (k/4)(\lambda_0 - \mu_0)^2\) where \(\lambda_0\) and \(\mu_0\) are the maximum and ...
openaire   +3 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source