Results 1 to 10 of about 2,054,558 (123)

Advances and perspectives of using stable isotope probing (SIP)-based technologies in contaminant biodegradation. [PDF]

Water Res X, 2023
Stable isotope probing (SIP) is a powerful tool to study microbial community structure and function in both nature and engineered environments. Coupling with advanced genomics and other techniques, SIP studies have generated substantial information to ...
Kim J, Hwangbo M, Shih CH, Chu KH.
europepmc   +4 more sources

HTSSIP: An R package for analysis of high throughput sequencing data from nucleic acid stable isotope probing (SIP) experiments. [PDF]

PLoS One, 2018
Combining high throughput sequencing with stable isotope probing (HTS-SIP) is a powerful method for mapping in situ metabolic processes to thousands of microbial taxa.
Youngblut ND, Barnett SE, Buckley DH.
europepmc   +4 more sources

High-Resolution Community Profiling of Active Bacteria and Eukaryotes in Replant-Diseased Blueberry Farm Soils From New Jersey, USA. [PDF]

Environ Microbiol
Long read bacterial and eukaryotic ribosomal operon sequencing combined with stable isotope probing (SIP) allowed the differentiation of microbiomes in low‐ and high‐yield blueberry farm soils. This report may ultimately be used to improve productivity and potentially detect the responsible pathogenic agent(s) or other deleterious microbes.
Mirzoyan S, Polashock JJ, Kerkhof LJ.
europepmc   +2 more sources

Marine Cold Seep ANME-2/SRB Consortia Produce Their Lipid Biomass From Inorganic Carbon. [PDF]

Environ Microbiol
Lipid‐stable isotope probing (SIP) experiments in Astoria Canyon sediments revealed that both ANME‐2 and SRB primarily assimilate dissolved inorganic carbon (DIC or HCO3‐), not methane, into biomass. SRB‐specific lipids showed eightfold higher DI13C‐assimilation than ANME lipids, suggesting SRB directly assimilate DIC, while ANME assimilate an ...
Stock L, Wegener G, Wang Y, Zander Y, Elvert M.   +4 more
europepmc   +2 more sources

SIP-SRS Imaging of Cell Wall Synthesis Identifies a Synergy between Micafungin and Amphotericin B. [PDF]

Adv Sci (Weinh)
We employed glucose‐d7–based stable isotope probe‐assisted SRS microscopy (SIP‐SRS) C–D imaging to visualize fungal cell wall synthesis and remodeling under antifungal treatment. Amphotericin B (AmB) induced notable daughter cell wall thickening, prompting a combinational therapy with AmB and micafungin.
Zhang M, Zhan Y, Lin H, Chen J, Seleem MN, Mansour M, Cheng JX.   +6 more
europepmc   +2 more sources

Metabolic pattern across energy imbalance: An exploratory metabolomics study of female body weight extremes including anorexia nervosa and athletes

Experimental Physiology, EarlyView.
Abstract In anorexia nervosa (AN), prolonged metabolic adaptation to severe energy deficiency can impair treatment efficacy. Similarly, low energy availability poses a recognized risk to athletes, potentially compromising health and performance. This cross‐sectional study aimed to characterize the plasma metabolic pattern of females with varying ...
Sonja Lackner, Olli Kärkkäinen, Sabrina Mörkl, Wolfram Müller, Alfred Fürhapter‐Rieger, Kati Hanhineva, Sandra Johanna Holasek   +6 more
wiley   +1 more source

High Tree Species Diversity Promotes Thermal Enhancement Response of Microbial Carbon Use Efficiency

Advanced Science, Volume 13, Issue 53, 24 September 2026.
ABSTRACT Predicting soil carbon dynamics under warming is constrained by limited understanding of microbial thermal adaptation, particularly whether microbial carbon use efficiency (CUE) can adapt to warming and how plant diversity modulates this response. Using soils from a natural tree species diversity gradient in a subtropical forest, we combined a
Pengpeng Duan, Changqing Ye, Xinyi Yang, Chaoqun Wang, Wolfgang Wanek, Jian‐sheng Ye, Hongzhao Yuan, Hu Du, Kongcao Xiao, Xunyang He, Kelin Wang, Dejun Li   +11 more
wiley   +1 more source

GLP‐1 Receptor Agonists and Endoscopy: Understanding Gastric Stasis, Aspiration Risk, and Contemporary Peri‐Procedural Guidance

Chronic Diseases and Translational Medicine, Volume 12, Issue 3, Page 183-196, September 2026.
Pharmacological mechanisms and physiologic effects of GLP‐1 receptor agonists relevant to peri‐endoscopic risk. ABSTRACT The global increase in obesity, type 2 diabetes mellitus (T2DM), and metabolic dysfunction‐associated steatotic liver disease (MASLD) has led to a higher use of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) among patients ...
Junaid Beig, Jason Ta, Sophie Jones, Emily Scott, Khalid Sofi, Frances Osler, Marije Jansen, Puneet Chhabra   +7 more
wiley   +1 more source

Simulated Root Exudation Gradient Reveals Dosage‐Dependent Carbon Sequestration in Desertification Ecosystems

Land Degradation &Development, Volume 37, Issue 15, Page 10640-10648, September 2026.
ABSTRACT Root exudates serve as a key driver for the restoration of soil organic carbon (SOC), particularly in aeolian desertification ecosystems where aboveground litter retention is limited. While Salix cupularis is widely planted as an effective pioneer shrub for ecological rehabilitation on the Qinghai‐Tibet Plateau, how the quantity of its root ...
Ran Xue, Xuemei Fang, Dongming Chen, Fei Yan, Aomei Jia, Zhouwen Ma, Yongheng Gao, Jiqiong Zhou, Jian Zhang, Lin Liu   +9 more
wiley   +1 more source

Strategies for Target Identification and Mechanism Elucidation in Phytochemicals

Phytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
Strategies for Target Identification of Phytochemicals: Labeling Methods VS. Non‐Labeling Methods ABSTRACT Drug targets serve as the fundamental biological basis through which phytochemicals exert their therapeutic effects, and target discovery represents both the core challenge and the rate‐limiting step in elucidating the mechanisms of action of ...
Jialing Chen, Yan Linghu, Dasong Wang, Weidong Pan, Kegang Linghu   +4 more
wiley   +1 more source