Results 91 to 100 of about 1,725,881 (271)
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
FEBS Open Bio, EarlyView.Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
The College Admissions problem with lower and common quotas [PDF]
, 2010 We study two generalised stable matching problems motivated by the current matching scheme used in the higher education sector in Hungary. The first problem is an extension of the College Admissions problem in which the colleges have lower quotas as well
Irving, R.W. +11 more
core +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Many allocation and matching problems (e.g., student-school assignments, job allocation, organ donation) involve coupling agents based on mutual preferences. A central requirement in matching problems is that of stability, that is classically defined as follows: a matching is stable if no blocking pair exists, where a blocking pair is a pair of agents ...
Fanelli, Angelo, Moscardelli, Luca
openaire +2 more sources
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Stability and Nash implementation in matching markets with couples [PDF]
We consider two-sided matching markets with couples. First, we extend a result by Klaus and Klijn (2005, Theorem 3.3) and show that for any weakly responsive couples market there always exists a "double stable" matching, i.e., a matching that is stable ...
Claus-Jochen Haake, Bettina Klaus
core +2 more sources
Stable Matchings with Covering Constraints: A Complete Computational Trichotomy. [PDF]
Algorithmica, 2020 Mnich M, Schlotter I.
europepmc +1 more source
Computing relaxations for the three-dimensional stable matching problem with cyclic preferences. [PDF]
Constraints, 2023 Cseh Á, Escamocher G, Quesada L.
europepmc +1 more source