Results 81 to 90 of about 1,725,881 (271)
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
CoRRWe show how fragile stable matchings are in a decentralized one-to-one matching setting. The classical work of Roth and Vande Vate (1990) suggests simple decentralized dynamics in which randomly-chosen blocking pairs match successively. Such decentralized interactions guarantee convergence to a stable matching.
openaire +2 more sources
Core Many-to-one Matchings by Fixed-point Methods [PDF]
We characterize the core many-to-one matchings as fixed points of a map. Our characterization gives an algorithm for finding core allocations; the algorithm is efficient and simple to implement.
Federico Echenique, Jorge Oviedo
core
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
The Stability of the Roommate Problem Revisited [PDF]
The lack of stability in some matching problems suggests that alternative solution concepts to the core might be applied to find predictable matchings. We propose the absorbing sets as a solution for the class of roommate problems with strict preferences.
Iñarra García, María Elena +2 more
core +2 more sources
Agreement toward stability in senior matching markets [PDF]
A stable matching disrupted by the retirement of workers or the opening, by firms, of positions is said to be firm quasi stable. We prove that, when firms have responsive preferences, the set of stable matchings unanimously preferred by workers to a ...
David Cantala
core
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Credible Group Stability in Many-to-Many Matching Problems [PDF]
It is known that in two-sided many-to-many matching problems, pairwise stable matchings may not be immune to group deviations, unlike in many- to-one matching problems (Blair 1988). In this paper, we show that pairwise stability is equivalent to credible
Hideo Konishi, M. Utku Ünver
core