Results 71 to 80 of about 1,725,881 (271)
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Rationalizability of one-to-one matchings with externalities [PDF]
In this paper, we show that the one-to-one matching model of Mumcu and Saglam (2008) studying stability under interdependent preferences is refutable. We also give a sufficient characterization of the set of matchings that are rationalizable inside the ...
Ismail Saglam, Ayþe Mumcu
core +2 more sources
CoRRIn bipartite matching problems, agents on two sides of a graph want to be paired according to their preferences. The stability of a matching depends on these preferences, which in uncertain environments also reflect agents' beliefs about the underlying state of the world. We investigate how a principal -- who observes the true state of the world -- can
Jonathan Shaki, Jiarui Gan, Sarit Kraus
openaire +2 more sources
Corrigendum: Stable Matchings and Preferences of Couples [PDF]
We correct an omission in the definition of the domain of weakly responsive preferences introduced in Klaus and Klijn (2005) or KK05 for short. The proof of the existence of stable matchings (KK05, Theorem 3.3) and a maximal domain result (KK05, Theorem ...
Nakamura, Toshifumi +2 more
core
Limited Randomness in Games, and Computational Perspectives in Revealed Preference [PDF]
, 2009 In this dissertation, we explore two particular themes in connection with the study of games and general economic interactions: bounded resources and rationality.
Kalyanaraman, Shankar
core +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Pareto optimality in house allocation problems [PDF]
, 2004 We study Pareto optimal matchings in the context of house allocation problems. We present an O(\sqrt{n}m) algorithm, based on Gales Top Trading Cycles Method, for finding a maximum cardinality Pareto optimal matching, where n is the number of agents and ...
Mehlhorn, K. +3 more
core +3 more sources
A Theory of Stability in Many-to-many Matching Markets [PDF]
We develop a theory of stability in many-to-many matching markets. We give conditions under which the setwise-stable set, a core-like concept, is nonempty and can be approached through an algorithm. The usual core may be empty.
Federico Echenique, Jorge Oviedo
core +2 more sources