Results 51 to 60 of about 339,506 (237)

Stable membrane topologies of small dual-topology membrane proteins [PDF]

open access: yes, 2017
AbstractThe topologies of α-helical membrane proteins are generally thought to be determined during their cotranslational insertion into the membrane. It is typically assumed that membrane topologies remain static after this process has ended. Recent findings, however, question this static view by suggesting that some parts of, or even the whole ...
Fluman, Nir   +2 more
openaire   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Uncovering the Relationship between Urban Road Network Topology and Taxi Drivers’ Income: A Perspective from Spatial Design Network Analysis

open access: yesISPRS International Journal of Geo-Information, 2022
Over the past few decades, taxi drivers’ income has received extensive attention from scholars. Previous studies have investigated the factors affecting taxi drivers’ income from multiple perspectives.
Changwei Yuan   +4 more
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Weak Convergence to Stable L\'evy Processes for Nonuniformly Hyperbolic Dynamical Systems [PDF]

open access: yes, 2013
We consider weak invariance principles (functional limit theorems) in the domain of a stable law. A general result is obtained on lifting such limit laws from an induced dynamical system to the original system.
Melbourne, Ian, Zweimüller, Roland
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Topology Control of Low-Connection UAV Laser Network with Virtual Nodes

open access: yesApplied Sciences
Space laser communication technology has advantages such as high bandwidth and low interference, but the limitation of the load capacity of an unmanned aerial vehicle (UAV) makes it difficult for UAV clusters to have sufficient communication links to ...
Pengyu Wang, Qingkui Li, Junkai Yi
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Formal analysis of control and termination of distributed computation in weaker spaces

open access: yesCogent Engineering, 2018
The control and termination detection of a distributed computation involving large-scale distributed database is difficult in the presence of concurrency, random network delays, and varying reliability of computing nodes. The formal modeling and analysis
Susmit Bagchi
doaj   +1 more source

Home - About - Disclaimer - Privacy