Results 41 to 50 of about 140,558 (270)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Research on the technical scheme of multi-stack common rail fuel cell engine based on the demand of commercial vehicle

open access: yesEnergy and AI
At present, most fuel cell engines are single-stack systems, and high-power single-stack systems have bottlenecks in meeting the power requirements of heavy-duty trucks, mainly because the increase in the single active area and the excessive number of ...
Ji Pu   +6 more
doaj   +1 more source

Energy harvesting from car suspension system: Mathematical approach for half car model

open access: yesJournal of Mechanical Engineering and Sciences, 2021
A significant contribution of this paper is developing a half car model with a built-in piezoelectric stack to evaluate the potential of harvesting power from the car suspension system.
Tariq Darabseh   +2 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

A Dimension-Reduced Artificial Neural Network Model for the Cell Voltage Consistency Prediction of a Proton Exchange Membrane Fuel Cell Stack

open access: yesApplied Sciences, 2022
The voltage consistency of hundreds of cells in a proton exchange membrane fuel cell stack significantly influences the stack’s performance and lifetime.
Jishen Cao   +5 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Design and Analysis of Transmission Optical Filter with Multi- FPR Structure for Dense Wavelength Division Multiplexing (DWDM) Communication System [PDF]

open access: yesEngineering and Technology Journal, 2014
In this paper, it is demonstrated by means of simulations, the practical feasibility of a transmission filter implemented from a stack of high and low index birefringent thin films. Simulations were carried out with a software toolbox package implemented
Aseel Abdul Ameer Shakaty
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The Impact of Ambient Temperature on Electrothermal Characteristics in Stacked Nanosheet Transistors with Multiple Lateral Stacks

open access: yesNanomaterials, 2023
With characteristic size scaling down to the nanoscale range, the confined geometry exacerbates the self-heating effect (SHE) in nanoscale devices. In this paper, the impact of ambient temperature (Tamb) on the SHE in stacked nanosheet transistors is ...
Peng Zhao   +4 more
doaj   +1 more source

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