Results 61 to 70 of about 6,373,106 (283)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
tum-gis/tum-gis-iot-stack-k8s: tum-gis-iot-stack-k8s-0.9.6
, 2023 Helm Chart for the TUM-GI IoT ...
Willenborg, Bruno +2 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Energy Efficient Clustering Based Network Protocol Stack for 3D Airborne Monitoring System
Journal of Computer Networks and Communications, 2017 Wireless Sensor Network consists of large number of nodes densely deployed in ad hoc manner. Usually, most of the application areas of WSNs require two-dimensional (2D) topology. Various emerging application areas such as airborne networks and underwater
Abhishek Joshi +4 more
doaj +1 more source
Design and Analysis of Transmission Optical Filter with Multi- FPR Structure for Dense Wavelength Division Multiplexing (DWDM) Communication System [PDF]
Engineering and Technology Journal, 2014 In this paper, it is demonstrated by means of simulations, the practical feasibility of a transmission filter implemented from a stack of high and low index birefringent thin films. Simulations were carried out with a software toolbox package implemented
Aseel Abdul Ameer Shakaty
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Simulation study of RCS/R-systems with several robots serving one picking station [PDF]
FME Transactions, 2023 Robot-based compact storage and retrieval systems (RCS/RS) are fully automatic storage systems operated by robots from above. Therein, goods are stored in plastic bins stacked on each other, resulting in a 'Last-In-First-Out' storage strategy within each
Trost Philipp +2 more
doaj
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
An Innovative Ensemble Deep Learning Clinical Decision Support System for Diabetes Prediction
IEEE AccessDiabetes is a significant global health concern, with an increasing number of diabetic people at risk. It is considered a chronic disease and leads to a significant number of fatalities annually.
Mana Saleh Al Reshan +6 more
doaj +1 more source