Results 81 to 90 of about 9,877,117 (330)

An Innovative Ensemble Deep Learning Clinical Decision Support System for Diabetes Prediction

IEEE Access
Diabetes is a significant global health concern, with an increasing number of diabetic people at risk. It is considered a chronic disease and leads to a significant number of fatalities annually.
Mana Saleh Al Reshan, Samina Amin, Muhammad Ali Zeb, Adel Sulaiman, Hani Alshahrani, Asadullah Shaikh, Mohamed A. Elmagzoub   +6 more
doaj   +1 more source

Activation of NF‐κB Signaling by Optogenetic Clustering of IKKα and β

Advanced Biology, EarlyView.
This study presents an optogenetic approach for graded clustering of eGFP‐fused proteins using an eGFP‐specific nanobody and engineered Cryptochrome 2 variants. The method enables potent, reversible activation of NF‐κB signaling via endogenous pathways, as confirmed by RNA sequencing. This versatile system provides a spatially and temporally controlled
Alexandra Anna Maria Fischer, Markus Michael Kramer, Miguel Baños, Merlin Moritz Grimm, Manfred Fliegauf, Bodo Grimbacher, Gerald Radziwill, Sven Rahmann, Wilfried Weber   +8 more
wiley   +1 more source

Defective and Clustered Choosability of Sparse Graphs

, 2019
An (improper) graph colouring has "defect" $d$ if each monochromatic subgraph has maximum degree at most $d$, and has "clustering" $c$ if each monochromatic component has at most $c$ vertices.
Hendrey, Kevin, Wood, David R.
core   +1 more source

Validation of finite-element models of persistent-current effects in Nb3Sn accelerator magnets [PDF]

, 2015
Persistent magnetization currents are induced in superconducting filaments during the current ramping in magnets. The resulting perturbation to the design magnetic field leads to field quality degradation, particularly at low field, where the effect is ...
Ambrosio, G, Chlachidze, G, Collings, EW, Di Marco, J, Dietderich, DR, Felice, H, Ghosh, AK, Godeke, A, Gourlay, SA, Marchevsky, M, Prestemon, SO, Sabbi, G, Sumption, MD, Velev, GV, Wang, X, Xu, X, Zlobin, AV   +16 more
core   +3 more sources

Numerical modelling of soldered superconducting REBCO stacks of tapes suggests strong reduction in cross-field demagnetization

Scientific Reports, 2023
Stacks of superconducting REBCO tapes (or “stacks”) can trap high magnetic fields, above 17 T. However, relatively low oscillating transverse magnetic fields can fully demagnetize the stacks.
Shuo Li, Enric Pardo
doaj   +1 more source

Using a Supramolecular Approach to Engineer Modular Hydrogel Platforms for Culturing Protoplasts – from General Tissue Engineering to Cellular Agriculture

Advanced Biology, EarlyView.
Using supramolecular monomers, various hydrogel culture systems were formulated to culture protoplasts; including 2D, 2.5D, and 3D hydrogels. Depending on the culture platform, bioactive functionalization led to protoplast enlargement (2D and 2.5D) or plasmolysis (3D). This work shows the potential to modularly engineer synthetic platforms for cellular
Maritza M. Rovers, Erik J. Slootweg, Ferdinand C. O. Los, Patricia Y. W. Dankers   +3 more
wiley   +1 more source

Modeling and Design of Container Terminal Operations [PDF]

, 2014
Design of container terminal operations is complex because multiple factors affect the operational perfor- mance. These factors include: topological constraints, a large number of design parameters and settings, and stochastic interactions that interplay
Koster, M.B.M. (René) de, Roy, D. (Debjit)   +1 more
core   +1 more source

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source