Results 41 to 50 of about 185,427 (266)
CrystalsThe crystal structures of the 2-amino-5-halogenopyridines (halogen = Cl (1), Br (2)) and 2,3-diamino-5-halogenopyridines (halogen = Cl (3), Br (4)) were compared with respect to their intermolecular interactions.
Irina S. Konovalova, Guido J. Reiss
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Hybrid Machine Learning Model for Efficient Botnet Attack Detection in IoT Environment
IEEE AccessCyber attacks are growing with the rapid development and wide use of internet technology. Botnet attack emerged as one of the most harmful attacks. Botnet identification is becoming challenging due to the numerous attack vectors and the ongoing evolution
Mudasir Ali +5 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Mapping stacks of topological stacks [PDF]
Journal für die reine und angewandte Mathematik (Crelles Journal), 2010 We prove that the mapping stack Map(Y,X) of topological stacks X and Y is again a topological stack if Y admits a compact groupoid presentation. If Y admits a locally compact groupoid presentation, we show that Map(Y,X) is a paratopological stack. In particular, it has a classifying space (hence, a natural weak homotopy type).
openaire +2 more sources
Crystal Engineering and Molecular Architecture [PDF]
Fanāvarī-i āmūzish, 2007 The aim of this paper is to provide a link between research projects and education to optimize teaching and learning of related subjects. In a research project, three compounds including an intermolecular proton transfer compound, a hydrated carboxylic ...
H. Aghabozorg +4 more
doaj
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
InformationThis study introduces BagStacking, an innovative ensemble learning framework designed to enhance the detection of freezing of gait (FOG) in Parkinson’s disease (PD) using accelerometer data.
Seffi Cohen +2 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source