Results 41 to 50 of about 186,103 (266)

Supramolecular Switching by Substituent Tuning: A Crystal Engineering Study of 2-Amino- and 2,3-Diamino-5-Halogenopyridines

Crystals
The crystal structures of the 2-amino-5-halogenopyridines (halogen = Cl (1), Br (2)) and 2,3-diamino-5-halogenopyridines (halogen = Cl (3), Br (4)) were compared with respect to their intermolecular interactions.
Irina S. Konovalova, Guido J. Reiss
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Hybrid Machine Learning Model for Efficient Botnet Attack Detection in IoT Environment

IEEE Access
Cyber attacks are growing with the rapid development and wide use of internet technology. Botnet attack emerged as one of the most harmful attacks. Botnet identification is becoming challenging due to the numerous attack vectors and the ongoing evolution
Mudasir Ali, Mobeen Shahroz, Muhammad Faheem Mushtaq, Sultan Alfarhood, Mejdl Safran, Imran Ashraf   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Crystal Engineering and Molecular Architecture [PDF]

Fanāvarī-i āmūzish, 2007
The aim of this paper is to provide a link between research projects and education to optimize teaching and learning of related subjects. In a research project, three compounds including an intermolecular proton transfer compound, a hydrated carboxylic ...
H. Aghabozorg, F. Manteghi, M. Ghadermazi, F. Mohammad Panah, S. Sheshmani   +4 more
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

BagStacking: An Integrated Ensemble Learning Approach for Freezing of Gait Detection in Parkinson’s Disease

Information
This study introduces BagStacking, an innovative ensemble learning framework designed to enhance the detection of freezing of gait (FOG) in Parkinson’s disease (PD) using accelerometer data.
Seffi Cohen, Nurit Cohen-Inger, Lior Rokach   +2 more
doaj   +1 more source

The Hilbert stack

Advances in Mathematics, 2014
Let π: X -> S be a morphism of algebraic stacks that is locally of finite presentation with affine stabilizers. We prove that there is an algebraic S-stack, the Hilbert stack, parameterizing proper algebraic stacks mapping quasi-finitely to X. This was previously unknown, even for a morphism of schemes.
Hall, Jack, Rydh, David
openaire   +4 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source