Results 71 to 80 of about 576,347 (278)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Prediction Method for Ocean Wave Height Based on Stacking Ensemble Learning Model

open access: yesJournal of Marine Science and Engineering, 2022
Wave heights are important factors affecting the safety of maritime navigation. This study proposed a stacking ensemble learning method to improve the prediction accuracy of wave heights. We analyzed the correlation between wave heights and other oceanic
Yu Zhan   +3 more
doaj   +1 more source

Detecting Electronic States at Stacking Faults in Magnetic Thin Films by Tunneling Spectroscopy

open access: yes, 2000
Co islands grown on Cu(111) with a stacking fault at the interface present a conductance in the empty electronic states larger than the Co islands that follow the stacking sequence of the Cu substrate.
A. L. Vázquez de Parga   +16 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Stacking-based and improved convolutional neural network: a new approach in rice leaf disease identification

open access: yesFrontiers in Plant Science, 2023
Rice leaf diseases are important causes of poor rice yields, and accurately identifying diseases and taking corresponding measures are important ways to improve yields. However, rice leaf diseases are diverse and varied; to address the low efficiency and
Le Yang   +6 more
doaj   +1 more source

Dynamical Stability of Slip-stacking Particles

open access: yes, 2014
We study the stability of particles in slip-stacking configuration, used to nearly double proton beam intensity at Fermilab. We introduce universal area factors to calculate the available phase space area for any set of beam parameters without individual
Eldred, Jeffrey, Zwaska, Robert
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

A Metamaterial Loaded High Gain Low Profile RHCP Microstrip Antenna for X-Band Applications

open access: yesIEEE Access
This paper presents the design of a right-hand circularly polarized (RHCP) microstrip antenna loaded with metamaterial to achieve high-gain performance.
Manoj Kumar Shrivastava   +5 more
doaj   +1 more source

Crystal structure of tetramethylammonium 1,1,7,7-tetracyanohepta-2,4,6-trienide

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2019
The title compound, C4H12N+·C11H5N4−, contains one tetramethylammonium cation and one 1,1,7,7-tetracyanohepta-2,4,6-trienide anion in the asymmetric unit. The anion is in an all-trans conjugated C=C bonds conformation.
Georgii Bogdanov   +4 more
doaj   +1 more source

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