Results 211 to 220 of about 180,508 (300)

Organizational Patient Safety Culture, Psychological Resilience, and Job Satisfaction Among Nurses in ISO-Certified and Non-ISO-Certified Departments: An Exploratory Cross-Sectional Comparison. [PDF]

Healthcare (Basel)
Manomenidis G, Gkotsidis K, Karavasileiadou S, Georgousopoulou V.   +3 more
europepmc   +1 more source

SPRED2 Negatively Regulates CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer

Advanced Science, EarlyView.
Sprouty‑related EVH1 domain containing 2 (SPRED2) restrains Ras/Raf/ERK signaling in CD8+ T cells. Host SPRED2 deficiency enhances T‐cell survival, cytotoxicity, and memory‐like phenotypes, reducing primary tumor growth and endpoint lung metastatic burden in breast cancer models.
Miao Tian, Teizo Yoshimura, Kun Zhao, Chunning Li, Tong Gao, Ziyi Wang, Masayoshi Fujisawa, Toshiaki Ohara, Akihiro Matsukawa   +8 more
wiley   +1 more source

Lion Hearts: applying implementation mapping to plan the delivery of a family-based physical activity intervention in community CrossFit affiliates. [PDF]

Front Public Health
Watkins J, Goss J, Mehls K, Marshall A, Dlugonski D, Downs DS.   +5 more
europepmc   +1 more source

A Robust Bio‐Supportive Hydrogel Patch for Full‐Thickness Repair of Gastroesophageal Defects

Advanced Science, EarlyView.
Gastroesophageal defect repair remains a formidable clinical challenge plagued by high leakage and life‐threatening complications. We develop a double‐disc, highly crystalline PVA‐based RBS hydrogel patch featuring suture‐free sealing, robust acid/enzyme resistance and mechanical durability.
Xingqi Song, Zhewei Shuai, Weiyan Sun, Liang Chen, Yiwei Shen, Jiateng Hu, Yuanqi Ma, Jie Luo, Meilin Huang, Yan Luo, Yunlang She, Guangdong Zhou, Chang Chen, Dong Lei   +13 more
wiley   +1 more source

Operational Challenges During Public Health Emergencies in Safety-Net Hospitals.

JAMA Netw Open
Sell TK, Grégoire V, Neufeld MS, Adler RR, Gosselin G, Pomer A, Tial BL, Weissman JS, Goralnick E.   +8 more
europepmc   +1 more source

Single‐Cell Transcriptomic Profiling Identifies B Cell‐Intrinsic Dysregulation of Sphingolipid Biosynthesis and Could Be Improved by Inhibiting UGCG in Primary Immune Thrombocytopenia

Advanced Science, EarlyView.
This study generates the single‐cell atlas of pathogenic B‐cell subset Bc‐5 in ITP. It identifies RUNX3 as a key survival regulator and uncovers sphingolipid‐driven metabolic reprogramming, validating UGCG inhibition as a therapeutic candidate and building a valuable resource for ITP mechanistic and therapeutic exploration.
Dongmei Luo, Yanxia Zhan, Lili Ji, Pengcheng Xu, Pu Chen, Hao Pang, Yunan Ling, Fanli Hua, Xibing Zhuang, Hao Chen, Yunfeng Cheng   +10 more
wiley   +1 more source

Staffing Audit Outcomes Among California Skilled Nursing Facilities, Prior to and After COVID-19-Related Staffing Waivers. [PDF]

J Am Med Dir Assoc
Cohen CC, Chiu HY, Chastain A, Perera UGE, Zhao S, Stone PW, Dick AW.   +6 more
europepmc   +1 more source

Gut Microbial Topology and Metabolic Signatures Associated With Colorectal Neoplasia

Advanced Science, EarlyView.
The gut microbiota organizes into two robust association patterns linked to colorectal neoplasia risk. Topological shifts in microbial networks are associated with metabolite alterations and may shape host responses during disease development. ABSTRACT Alterations of gut microbial communities impact health.
Kai Song, Youwen Qin, Jiahui Luo, Liping Liu, Chenyu Luo, Yinbin Qiu, Yiyi Zhong, Huanzi Zhong, Kui Wu, Meng Ni, Dong Wu, Min Dai, Shida Zhu, Hongda Chen   +13 more
wiley   +1 more source

A Comparative Analysis of Multi-Criteria Decision-Making Methods and Workload Indicators of Staffing Need in Estimating the Number of Information Technology Experts Needed for District Health Networks: A Descriptive-Analytical Study. [PDF]

Health Sci Rep
Jangi M, Babokani AS, Masoudi MH, Rezaei M, Najafabadi NG, Kazemzadeh M.   +5 more
europepmc   +1 more source