Results 61 to 70 of about 143,244 (309)
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Factors affecting subsidiary staffing of Japanese multinationals: a panel data analysis
, 2020 Global staffing is a crucial factor for the success of the overseas operations of multinational corporations (MNCs). This study examines the contextual and organisational factors that affect the localisation of subsidiary staffing in the overseas ...
Ando, Naoki +2 more
core +1 more source
, 2021 In Queensland (Australia), community-based residential mental health rehabilitation services have three distinct staffing profiles. The traditional 'clinical' staffing model has nursing staff occupying most staff roles.
Karan, Nirvana +3 more
core +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
, 2022 This observational study compared the outcomes of consumers receiving community-based residential mental health rehabilitation support in Australia under a clinical staffing model and an integrated staffing model where Peer Support Workers are the ...
Korman, N +4 more
core +1 more source
The ways of preventing drug use by military personnel of military organizations [PDF]
علوم و فنون نظامی, 2019 • Currently, drug addiction and drug use as one of the most serious social challenges in our country are the cause of many injuries and deviations, and employees working in military organizations as part of Society is naturally exposed to the tendency to
javad abdi
doaj
FEBS Open Bio, EarlyView.The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
The Effect of Hospital Nurse Staffing on Patient Health Outcomes: Evidence from California's Minimum Staffing Regulation [PDF]
Hospitals are currently under pressure to control the cost of medical care, while at the same time improving patient health outcomes. These twin concerns are at play in an important and contentious decision facing hospitals—choosing appropriate nurse ...
Andrew Cook +3 more
core
Russian and regional performance indices of local therapists
Терапевтический архив, 2015 Aim. To analyze the statistical indicators of a local therapist's performance in the Russian Federation and its districts in the 2008-2012 period. Materials and methods.
V I Starodubov +3 more
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