Results 121 to 130 of about 5,493,736 (306)
Design and performance of a high-pressure-ratio, highly loaded axial-flow transonic compressor space [PDF]
A 50-cm-diam. axial-flow transonic compressor stage with multiple-circular-arc blades was designed and tested. At design speed, a rotor peak efficiency of 0.85 occurred at an equivalent weight flow of 29.3 kg/sec.
Lewis, G. W., Jr., Reid, L., Tysl, E. R.
core +1 more source
Coupling methods for multistage sampling
, 2015 Multistage sampling is commonly used for household surveys when there exists no sampling frame, or when the population is scattered over a wide area. Multistage sampling usually introduces a complex dependence in the selection of the final units, which ...
Chauvet, Guillaume
core +3 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Sampling statistics in the Atlantic menhaden fishery [PDF]
, 1984 Atlantic menhaden, Brrvoortia tyrannus, the object of a major purse-seine fishery along the U.S. east coast, are landed at plants from northern Florida to central Maine.
Chester, Alexander J.
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Design and cold-air investigation of a turbine for a small low-cost turbofan engine [PDF]
An 8.00-in mean diameter two-stage turbine was investigated over a range of speeds from 0 to 110 percent of equivalent design speed and over a range of pressure ratios from 1.79 to 5.14.
Kofskey, M. G., Nusbaum, W. J.
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
10th Anniversary of a Two-Stage Design in Bioequivalence. Why Has it Still Not Been Implemented? [PDF]
Pharm Res, 2020 Kaza M, Sokolovskyi A, Rudzki PJ.
europepmc +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Overall and blade element performance of a 1.20 pressure ratio fan stage with rotor blades reset -7 deg [PDF]
A 51-cm-diam model of a fan stage for short haul aircraft was tested in a single stage compressor research facility. The rotor blades were set 7 deg toward the axial direction (opened) from the design setting angle.
Kovich, G., Lewis, G. W., Jr.
core +1 more source