Engineering design project : series 1 [PDF]
This book is a compilation of engineering design projects which illustrates a detail explanation on the design process including all tools and methods involved in each design stage.
core
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Adapting Simon's Two-Stage Design for Efficient Screening of Filovirus Vaccines in Non-Human Primates. [PDF]
Niemuth NA, Sabourin CL, Ward LA.
europepmc +1 more source
Performance of single-stage axial-flow transonic compressor with rotor and stator aspect ratios of 1.63 and 1.77, respectively, and with design pressure ratio of 2.05 [PDF]
The overall and blade-element performance of a transonic compressor stage is presented over the stable operating range for speeds from 50 to 100 percent of design.
Moore, R. D., Reid, L.
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Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
A stratified adaptive two-stage design with co-primary endpoints for phase II clinical oncology trials. [PDF]
Cabarrou B +4 more
europepmc +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A batch-effect adjusted Simon's two-stage design for cancer vaccine clinical studies. [PDF]
Wang C +5 more
europepmc +1 more source
Two-Stage Beamformer Design for Massive MIMO Downlink By Trace Quotient Formulation
In this paper, the problem of outer beamformer design based only on channel statistic information is considered for two-stage beamforming for multi-user massive MIMO downlink, and the problem is approached based on signal-to-leakage-plus-noise ratio ...
Kim, Donggun +2 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

