Results 81 to 90 of about 1,445,084 (280)
Images, 2016 Working on the role –Richard III The author describes the contexts for working on the title role of Shakespeares Richard III. He points to specific stages in working on the role: familiarising oneself with the original text and associated literature ...
MAREK KAŁUŻYŃSKI
doaj +1 more source
Video Description using Bidirectional Recurrent Neural Networks
, 2016 Although traditionally used in the machine translation field, the encoder-decoder framework has been recently applied for the generation of video and image descriptions.
Bolaños, Marc +3 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
, 2019 Cross-view image translation is challenging because it involves images with drastically different views and severe deformation. In this paper, we propose a novel approach named Multi-Channel Attention SelectionGAN (SelectionGAN) that makes it possible to
Corso, Jason J. +5 more
core +1 more source
Clinical and molecular features and therapeutic perspectives of spinal muscular atrophy with respiratory distress type 1 [PDF]
, 2015 Spinal muscular atrophy with respiratory distress (SMARD1) is an autosomal recessive neuromuscular disease caused by mutations in the IGHMBP2 gene, encoding the immunoglobulin μ-binding protein 2, leading to motor neuron degeneration.
Corti, Stefania +4 more
core +2 more sources
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Anusaaraka: Machine Translation in Stages
, 2003 Fully-automatic general-purpose high-quality machine translation systems (FGH-MT) are extremely difficult to build. In fact, there is no system in the world for any pair of languages which qualifies to be called FGH-MT. The reasons are not far to seek.
Bharati, Akshar +3 more
openaire +2 more sources
Facilitating stakeholder engagement in early stage translational research
PLOS ONE, 2020 Stakeholder engagement can play an important role in increasing public trust and the understanding of scientific research and its impact. Frameworks for stakeholder identification exist, but these frameworks may not apply well to basic science and early stage translational research.Four Clinical and Translational Science Award (CTSA) hubs led six focus
Amy M. LeClair +6 more
openaire +4 more sources
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source