Results 241 to 250 of about 469,197 (318)

Augmenting Large Language Model With Prompt Engineering and Supervised Fine-Tuning in Non-Small Cell Lung Cancer Tumor-Node-Metastasis Staging: Framework Development and Validation. [PDF]

JMIR AI
Jin R, Ling C, Hou Y, Sun Y, Li N, Han J, Sheng J, Wang Q, Liu Y, Zheng S, Ren X, Chen C, Wang J, Li C.   +13 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Debate: why surgery should remain central in the management of locally advanced (Stage III) non-small-cell lung cancer. [PDF]

BJC Rep
Aboujudom C, Nelson DB, Sarkaria I, Kernstine KH.   +3 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Computed tomography staging of colon cancer: improved patient selection for neoadjuvant therapy with combined radiologic tumor and nodal staging. [PDF]

BMC Cancer
Lee S, Yu J, Kampalath R, Castillo O, Sandhu J, Tajik F, Ostowari A, Kirby KA, Dehkordi-Vakil FH, Chantaduly C, Chang PD, Vilchez V, Straker RJ, Whealon MD, Krishnamurthi SS, Maithel SK, Stamos MJ, Senthil M.   +17 more
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Beyond the Surface: Duodenal-Type Follicular Lymphoma Diagnosed Despite Normal-Appearing Duodenal Mucosa and Absence of Focal Duodenal FDG Uptake. [PDF]

Case Rep Gastrointest Med
Vinton Z, Schulz C, McGuire W, Hafeez S, Malik S.   +4 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Utilizing [¹⁸F]-FDG PET/CT Imaging for Enhanced Staging and Treatment Decisions in Pediatric Rhabdomyosarcoma. [PDF]

Cancers (Basel)
Halalsheh H, Odeh N, Kiswani A, Alzoubi M, Diab A, Al-Assaf N, Al-Ibraheem A, Ibrahimi AK, Boheisi M, Sultan I.   +9 more
europepmc   +1 more source