The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
A Case of Unresectable Ampulla of Vater Carcinoma Successfully Treated with Conversion Surgery Following Sequential Systemic Chemotherapy Including Durvalumab. [PDF]
Araki T +13 more
europepmc +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
A systematic review of staging systems for oral submucous fibrosis: evolution, variations, and clinical implications. [PDF]
Shetty P +5 more
europepmc +1 more source
Diagnostic Concordance Between Contrast-Enhanced CT and Bone Scintigraphy for Detecting Bone Metastases in Clinical T3/N1 Breast Cancer. [PDF]
Khan H, Hidayat M, Arif H, Rehman B.
europepmc +1 more source
Mesonephric-Like Adenocarcinoma of the Endometrium and the Impact of the Updated 2023 FIGO Staging System. [PDF]
Ogunmuyiwa J +6 more
europepmc +1 more source
Diagnostic accuracy of magnetic resonance imaging for rectal cancer: is it time to reassess the gold standard? [PDF]
Huei TJ, Wei EJTK.
europepmc +1 more source
High-Frequency Miniprobe Endoscopic Ultrasonography Across the Gastrointestinal Tract. [PDF]
Bombaci F +10 more
europepmc +1 more source

