Results 251 to 260 of about 879,906 (340)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

⁶⁸Ga-PSMA-11 in Staging of Unfavorable Intermediate- and High-Risk Prostate Cancer Reduces Indication for Noncurative Prostatectomy: A Prospective, Multicenter, IAEA Study. [PDF]

J Nucl Med
Cerci JJ, Fanti S, Lobato EE, Kumar R, Kunikowska J, Al-Ibraheem A, Nasir M, Redondo Moneda F, Garcia O, Haidar M, Novruzov F, Kucuk O, Elboga U, de Almeida Luz M, Paez D.   +14 more
europepmc   +1 more source

Serum Bone Morphogenetic Proteins, Hepcidin ,Ferroportin , Chitotriosidase and Alkaline Phosphatase Activity as Tumor Markers in Detection and Staging of Breast Cancer

Hatem Ali, Furat Y. Mohsen, Zahraa Ali
openalex   +1 more source

The impact of ipsilateral central neck dissection on the 2015 American thyroid association risk stratification system and TNM staging in papillary thyroid carcinoma

, 2019
Gustavo Penna, Patricia Freitas Corradi, Henrique G. Mendes, Cynthia Koeppel Berenstein, Magda Carvalho Pires, Bernardo Fonseca, Gustavo Meyer de Moraes   +6 more
openalex   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Development and validation of a risk prediction model for overall survival in cervical cancer patients under 50: a prospective cohort study in southwest China. [PDF]

PeerJ
Yuan L, Wen B, Li X, Liu F, Lei H, Zhou Q.   +5 more
europepmc   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

CT staging performance in an international trial of neoadjuvant chemotherapy for locally advanced colon cancer. [PDF]

Br J Radiol
Platt JR, Elliott F, Handley K, Magill L, Quirke P, Seymour MT, West NP, Morton D, Seligmann J, Tolan DJM.   +9 more
europepmc   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Pathological Upgrading and Up Staging With Immediate Repeat Biopsy in Patients Eligible for Active Surveillance

, 2008
Ryan K. Berglund, Timothy A. Masterson, Kinjal Vora, Scott E. Eggener, James A. Eastham, Bertrand Guillonneau   +5 more
openalex   +1 more source