Results 71 to 80 of about 469,197 (318)

gCube Portal Staging

, 2018
gCube Portal Staging <br> <br><strong>Support</strong> <br> Bugs and support requests can be reported in the gCube issue tracking tool:<br> <a href="https://support.d4science.org/projects/gcube/">https ...
Massimiliano Assante (5203816), Massimiliano Assante   +1 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Empowering Potential of Re-Staging

, 2012
In this paper we present and discuss the empowering potential of re- staging interactive art installations. We build on an approach, where we divide the staging process into four levels of staging (potential, strategic, tactical, dynamic), and in Umberto
Cappelen , Birgitta, Andersson, Anders-Petter   +1 more
core   +1 more source

Factors affecting accuracy of clinical staging in resectable non‐small cell lung cancer in a real‐world study

Thoracic Cancer
Background The clinical staging of non‐small cell lung cancer (NSCLC) is well known to be related to their prognosis. However, there is usually a discrepancy between clinical staging and pathological staging.
Hye Ran Gwon, A. La Woo, Seung Hyun Yong, Youngmok Park, Song Yee Kim, Eun Young Kim, Ji Ye Jung, Young Ae Kang, Moo Suk Park, Seong Yong Park, Sang Hoon Lee   +10 more
doaj   +1 more source

Staging of suicidality in bipolar disorder: Findings from the FACE-BD cohort (FondaMental Advanced Centers of Expertise for Bipolar Disorders)

European Psychiatry
Introduction Suicidal behaviors (SB) in bipolar disorder (BD) are major adverse outcomes that may influence disease progression. While staging models exist for psychiatric disorders, none include suicide.
Anna Maria Auxilia, Emilie Olié, Jonathan Dubois, Enrico Capuzzi, Valérie Aubin, Bruno Aouizerate, Frank Bellivier, Raoul Belzeaux, Caroline Dubertret, Dominique Januel, Emmanuel Haffen, Antoine Lefrere, Agnès Pelletier, Mircea Polosan, Roman Rey, Paul Roux, Ludovic Samalin, Raymund Schwan, Michel Walter, Antoine Yrondi, FondaMental Advanced Centers of Expertise in Bipolar Disorders (FACE-BD) Collaborators, Pierre Michel Llorca, Marion Leboyer, Bruno Etain, Philippe Courtet   +24 more
doaj   +1 more source

Diagnosis and staging of laryngopharyngeal tumours with flexible endoscopy: A prospective study

South African Journal of Oncology, 2019
Background: Many suspected laryngopharyngeal neoplasms are examination under general anaesthesia (EUA). Office-based endoscopy is already routinely performed on all patients presenting with a suspected laryngopharyngeal neoplasm.
Hendrik K. Uys, Andrew Pelser, Rory Attwood, Shaun Adam, Amir Afrogheh, Jos Hille, James W. Loock   +6 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Histopathological report of colorectal carcinoma resections: A 5-year audit in Lagos

Nigerian Postgraduate Medical Journal, 2018
Background: Complete and accurate pathology reporting of colorectal carcinoma (CRC) resection specimen is critical to clinical management of individual patients. The study aims to audit colorectal cancer histopathology reporting in Lagos between 2011 and
Kabir Bolarinwa Badmos, Olorunda Rotimi, Abdulrazzaq Oluwagbemiga Lawal, Adedapo O Osinowo, Mohammed Y Habeebu, Fatimah Biade Abdulkareem   +5 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Hepatocellular carcinoma: Epidemiology, diagnosis and treatmentKeypoints

JHEP Reports
Summary: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related mortality worldwide and primarily affects individuals with cirrhosis.
Ezequiel Mauro, Tiago de Castro, Marcus Zeitlhoefler, Max W. Sung, Augusto Villanueva, Vincenzo Mazzaferro, Josep M. Llovet   +6 more
doaj   +1 more source