Results 91 to 100 of about 892,678 (358)
Hepatocellular carcinoma: Epidemiology, diagnosis and treatmentKeypoints
JHEP ReportsSummary: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related mortality worldwide and primarily affects individuals with cirrhosis.
Ezequiel Mauro +6 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Immunophenotyping of male breast cancer - Experience at a tertiary care centre
Indian Journal of Pathology and Microbiology, 2019 Background: Male breast cancers (MBCs) are uncommon and account for 1% of all breast cancers. Medical conditions that increase the estrogen to testosterone ratio are implicated as the risk factors.
Sunil Pasricha +7 more
doaj +1 more source
How to Hold a Press Conference [PDF]
, 2013 Media relations students gain real-world experience by staging a mock press conference to address recent issues at Carnival Cruise ...
Rodrigues, Jill
core +1 more source
Evidence-based indications for the planning of PET or PET/CT capacities are needed [PDF]
, 2019 Purpose To identify evidence-based indications for PET/PET–CT scans in support of facilities planning and to describe a pilot project in which this information was applied for an investment decision in an Austrian region.
Busse, Reinhard +4 more
core +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
NELFE-Dependent MYC Signature Identifies a Unique Cancer Subtype in Hepatocellular Carcinoma. [PDF]
, 2019 The MYC oncogene is dysregulated in approximately 30% of liver cancer. In an effort to exploit MYC as a therapeutic target, including in hepatocellular carcinoma (HCC), strategies have been developed on the basis of MYC amplification or gene ...
Bodzin, Adam S. +9 more
core +3 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Specular suffering: (staging) the body in pain [PDF]
, 2008 For the abstract see the PDF ...
Richards, M
core
Current Opinion in Neurobiology, 2020 Staging of neurodegenerative diseases is based chiefly on the topographical or anatomical extent of aggregated proteinaceous inclusions, and the density or severity of the lesions in a given region is usually assessed semiquantitatively. Associated phenomena, such as cell loss and synapse loss, are evaluated but not staged.
Kelly, Del Tredici, Heiko, Braak
openaire +2 more sources