Results 91 to 100 of about 469,197 (318)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Locally Advanced Cervical Cancer: Multiparametric MRI in Gynecologic Oncology and Precision Medicine

Diagnostics
Background: Locally advanced cervical cancer (LACC) represents a significant challenge in oncology, requiring accurate assessment of local extent and metastatic spread.
Sara Boemi, Matilde Pavan, Roberta Siena, Carla Lo Giudice, Alessia Pagana, Marco Marzio Panella, Maria Teresa Bruno   +6 more
doaj   +1 more source

Symptom-based staging for logopenic variant primary progressive aphasia [PDF]

Background and purpose Logopenic variant primary progressive aphasia (lvPPA) is a major variant presentation of Alzheimer's disease (AD) that signals the importance of communication dysfunction across AD phenotypes.
Thompson, L., Marshall, C.R., Harding, E., Oxtoby, N.P., Taylor-Rubin, C., Chokesuwattanaskul, A., Stott, J., Wood, O., Kupeli, N., Hardy, C.J.D., Rohrer, J.D.,, Walker, F., Waddington, C., Zimmermann, N., Crutch, S.J., Barker, S., Warren, J.D., Jiang, J., Volkmer, A., Camic, P.M., Brotherhood, E., Taylor, B., Yong, K.X.X., Suarez Gonzalez, A., Kingma, R.   +24 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Automated Lymph Node Localization and Segmentation in Patients with Head and Neck Cancer: Opportunities and Limitations of Using a Generic AI Model

Diagnostics
Background/Objectives: Accurate assessment of lymph nodes is of paramount importance for correct cN staging in head and neck cancer; however, it is very time-consuming for radiologists, and lymph node metastases of head and neck cancers may show distinct
Miriam Rinneburger, Heike Carolus, Andra-Iza Iuga, Mathilda Weisthoff, Simon Lennartz, Nils Große Hokamp, Liliana Lourenco Caldeira, Astha Jaiswal, David Maintz, Fabian Christopher Laqua, Bettina Baeßler, Tobias Klinder, Thorsten Persigehl   +12 more
doaj   +1 more source

Comparison of the 7th and 8th Edition of the UICC/AJCC TNM Staging System in Primary Resected Squamous Cell Carcinomas of the Lung—A Single Center Analysis of 354 Cases

Frontiers in Medicine, 2019
Background: The AJCC/UICC TNM (tumor, node, metastasis) classification is a standardized system for the description of anatomical extent and stage grouping of solid malignant tumors and is regularly updated.
Christina Neppl, Manuel D. Keller, Amina Scherz, Patrick Dorn, Ralph A. Schmid, Inti Zlobec, Sabina Berezowska   +6 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Classification and staging of retinoblastoma. [PDF]

, 2018
Classifying and staging retinoblastoma is an essential first step when planning how to manage a child with the condition; it also gives important information about prognosis.
Mandeep S Sagoo, Fabian, ID, Reddy, A, Ido Didi Fabian, Sagoo, MS, Ashwin Reddy   +5 more
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Analysis of the Stage [PDF]

Schedae Informaticae, 2009
The primary objective of this paper is to design a method of de- tecting road edges without using complex algorithms to identify and analyze images. Instead, neural networks are used, which allows to enhance and facil- itate this process. The paper describes a program that recognizes the road in a picture with the use of a neural network trained on 500
openaire   +2 more sources