Results 101 to 110 of about 469,197 (318)

On Stage, But Not on Cue

open access: yesAMA Journal of Ethics, 2023
This comic considers how patients can work to use the right vocabulary to help their physicians help them, since patients suffer when physicians fail to properly diagnose and intervene on their ailments. This comic also considers how patients can experience performance anxiety after what might be months of preparation for a key clinic visit in hopes of
openaire   +2 more sources

The IASLC Lung Cancer Staging Project : a renewed call to participation

open access: yes, 2018
: Over the past two decades, the International Association for the Study of Lung Cancer (IASLC) Staging Project has been a steady source of evidence-based recommendations for the TNM classification for lung cancer published by the Union for International
Kernstine, Kemp   +7 more
core  

Application of Pathological Staging in Esophageal Squamous Cell Carcinoma

open access: yes, 2020
Pathological staging is the most important factor that determines the prognosis and management of patients with esophageal squamous cell carcinoma. The method for the pathological staging in esophageal squamous cell carcinoma involves assessment of ...
Lam, AK, Alfred K. Lam
core   +1 more source

Staging of neurofibrillary pathology in Alzheimer's disease : a study of the BrainNet Europe Consortium [PDF]

open access: yes, 2008
It has been recognized that molecular classifications will form the basis for neuropathological diagnostic work in the future. Consequently, in order to reach a diagnosis of Alzheimer's disease (AD), the presence of hyperphosphorylated tau (HP-tau) and ...
Meyronet, David   +98 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

TNM cancer staging: can it help develop a novel staging system for type 2 diabetes?

open access: yes, 2018
Moahad S Dar,1,2 Sami A Bég3 1Department of Veteran Affairs, Greenville Health Care Center, Greenville, NC, USA; 2Division of Endocrinology & Metabolism, Department of Internal Medicine, Brody School of Medicine at East Carolina University ...
Dar MS, Bég SA
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

METHOD OF CASE MODELING

open access: yesВысшее образование в России, 2018
The article presents the method of case modeling used in the process of education within the programs of higher humanitarian education. The author dwells on the problems of current learning methods, as well as on the existing methods of their solution ...
P. N. Vishnevskiy
doaj  

Pathological, immunological and molecular epidemiological analysis of lumpy skin disease virus in Indian cattle during a high-mortality epidemic

open access: yesVeterinary Quarterly
Lumpy skin disease (LSD) is an economically significant, emerging viral disease of Cattle and Buffaloes. This study aimed to investigate the causes of high mortality in a recent LSD epidemic in India. We examined 1618 animals across seventy outbreaks and
Gundallhalli Bayyappa Manjunathareddy   +7 more
doaj   +1 more source

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