Results 101 to 110 of about 892,678 (358)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Definition, Epidemiology and Pathophysiology of Lymphoedema

Cells
Lymphoedema is a physically and psychologically stressful, chronic progressive disease caused by long lasting damage or malfunction of the lymphatic drainage system.
Erich Brenner, René Hägerling, Vivien Schacht, Klaus Schrader, Jörg Wilting   +4 more
doaj   +1 more source

Time-Staging Enhancement of Hybrid System Falsification

, 2018
Optimization-based falsification employs stochastic optimization algorithms to search for error input of hybrid systems. In this paper we introduce a simple idea to enhance falsification, namely time staging, that allows the time-causal structure of time-
Ernst, Gidon, Hasuo, Ichiro, Sedwards, Sean, Zhang, Zhenya   +3 more
core  

Staging quantum cryptography with chocolate balls

, 2005
Moderated by a director, laymen and students are encouraged to assume the role of quanta and enact a quantum cryptographic protocol. The performance is based on a generalized urn model capable of reproducing complementarity even for classical chocolate ...
Svozil, Karl
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Locally Advanced Cervical Cancer: Multiparametric MRI in Gynecologic Oncology and Precision Medicine

Diagnostics
Background: Locally advanced cervical cancer (LACC) represents a significant challenge in oncology, requiring accurate assessment of local extent and metastatic spread.
Sara Boemi, Matilde Pavan, Roberta Siena, Carla Lo Giudice, Alessia Pagana, Marco Marzio Panella, Maria Teresa Bruno   +6 more
doaj   +1 more source

On the role of depletive tests. a review analysis [PDF]

, 2016
An overview of the diagnostic role of depletion tests for staging Meniere’s disease, especially in the first phase of the disease, is reported.
Barbara, M, Covelli, E, Marrone, V, Monini, S, Tarentini, S   +4 more
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Automated Lymph Node Localization and Segmentation in Patients with Head and Neck Cancer: Opportunities and Limitations of Using a Generic AI Model

Diagnostics
Background/Objectives: Accurate assessment of lymph nodes is of paramount importance for correct cN staging in head and neck cancer; however, it is very time-consuming for radiologists, and lymph node metastases of head and neck cancers may show distinct
Miriam Rinneburger, Heike Carolus, Andra-Iza Iuga, Mathilda Weisthoff, Simon Lennartz, Nils Große Hokamp, Liliana Lourenco Caldeira, Astha Jaiswal, David Maintz, Fabian Christopher Laqua, Bettina Baeßler, Tobias Klinder, Thorsten Persigehl   +12 more
doaj   +1 more source

Comparison of the 7th and 8th Edition of the UICC/AJCC TNM Staging System in Primary Resected Squamous Cell Carcinomas of the Lung—A Single Center Analysis of 354 Cases

Frontiers in Medicine, 2019
Background: The AJCC/UICC TNM (tumor, node, metastasis) classification is a standardized system for the description of anatomical extent and stage grouping of solid malignant tumors and is regularly updated.
Christina Neppl, Manuel D. Keller, Amina Scherz, Patrick Dorn, Ralph A. Schmid, Inti Zlobec, Sabina Berezowska   +6 more
doaj   +1 more source