Results 111 to 120 of about 469,197 (318)

HIV/AIDS clinical manifestations and their implication for patient clinical staging in resource limited settings in Tanzania [PDF]

, 2011
BACKGROUND: Tanzania HIV/AIDS management follows WHO clinical staging which requires CD4 counts as complement. Lacking CD4 counts facilities in rural health facilities remains a challenge. Simplified and sensitive clinical staging based on local clinical
Mugusi, F., Rumisha, S. F., Tanner, M., Omari, Minzi, Marcel, Tanner, Omari, M., Idindili, B., Susan Fred, Rumisha, Ferdinand, Mugusi, Idindili Boniphace, Minzi, O., Boniphace, Idindili, Rumisha, S.F.   +12 more
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Staging Ajax's suicide /

, 2015
"This volume collects the contributions presented and discussed in the international conference "Staging Ajax's Suicide" held at the Scuola Normale Superiore on 7-9 November 2013.
Ozbek, Leyla,edt, Most, Glenn W.(viaf)108445936, Staging Ajax's Suicide (Conference)(2013 :Scuola normale superiore)   +2 more
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

L’écriture théâtrale de la crise des races : le paradigme historique du racisme dans La Croix du Sud de Joseph Ngoué [PDF]

Revue Roumaine d’Etudes Francophones
The crisis faced by societies of truly established racial segregation deserves particular attention in the literaryspace, and its writing requires in-depth analysis within the field of criticism.
Jean Boris TENFACK MELAGHO
doaj  

Need for Staging Investigations in Newly Diagnosed Breast Cancer: Establishing Local Guidelines for Radiological Staging in Bahrain

Objective: Staging workup and detection of distant metastases is important in newly diagnosed breast cancer in order to make treatment decisions and establish the prognosis. There is wide variation in current recommendations for staging investigations in
Aysha Adnan Alsadoon, Tareq Hamed Altaei, Raja Eid, Noora Fuad Ali, Hussain Adnan Abdulla, Ahmed Zuhair Salman, Wegdan Zaki Albati, Ahmed Adel Alkazaz, Hisham Mustafa Habib, Sayed Ali Almahari, Noor Ali Almawlani, Fatema Ali Alkhabbaz   +11 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

gCube 4.0.0 - gCube Portal Staging v. 2.0.0

, 2016
<p> The gCube System - gCube Portal Staging<br> --------------------------------------------------<br> <br> gCube Portal Staging<br> <br> <br> This software is part of the gCube Framework (https://www.gcube ...
Massimiliano Assante (5203816), Massimiliano Assante   +1 more
core   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

vNOTES retroperitoneal sentinel lymph node dissection for endometrial cancer staging: First multicenter, prospective case series

Acta Obstetricia et Gynecologica Scandinavica
Introduction The current standard treatment for endometrial cancer is a laparoscopic hysterectomy with adnexectomies and bilateral sentinel node resection.
Jan Baekelandt, Astrid Jespers, Daniela Huber, Levon Badiglian‐Filho, Andrea Stuart, Linus Chuang, Oudai Ali, Alexander Burnett   +7 more
doaj   +1 more source