Results 81 to 90 of about 469,197 (318)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Immunophenotyping of male breast cancer - Experience at a tertiary care centre
Indian Journal of Pathology and Microbiology, 2019 Background: Male breast cancers (MBCs) are uncommon and account for 1% of all breast cancers. Medical conditions that increase the estrogen to testosterone ratio are implicated as the risk factors.
Sunil Pasricha +7 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Staged Computation with Staged Lexical Scope [PDF]
, 2012 We present a simple core type system, λ[ ] -- pronounced "lambda open box" -- for a statically typed, hygienic, and multi-stage lambda-calculus supporting evaluation under future-stage binders, open-code manipulation, a first-class eval function, and mutable state.
openaire +1 more source
Pancreatic neuroendocrine neoplasms: Clinicopathological features and pathological staging.
, 2020 The nomenclature and classification of pancreatic neuroendocrine neoplasms has evolved in the last 15 years based on the advances in knowledge of the genomics, clinical behaviour and response to therapies.
Lam, Alfred King-Yin, Ishida, Hirotaka
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Definition, Epidemiology and Pathophysiology of Lymphoedema
CellsLymphoedema is a physically and psychologically stressful, chronic progressive disease caused by long lasting damage or malfunction of the lymphatic drainage system.
Erich Brenner +4 more
doaj +1 more source
Staging Violence Against Women and Girls: Plays and Interviews
, 2023 Staging Violence Against Women and Girls brings together three contemporary plays that denounce gendered violence, along with interviews with their creators and the practitioners who have staged them in different national contexts.
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core
FIGO staging of endometrial cancer: 2023
, 2023 INTRODUCTION: Many advances in the understanding of the pathologic and molecular features of endometrial cancer have occurred since the FIGO staging was last updated in 2009.
Christina Fotopoulou +22 more
core +2 more sources