Results 31 to 40 of about 382,148 (218)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
« Écrans de lumière » : l’art du vitrail dans l’architecture de Frank Lloyd Wright
E-REA, 2023 This article will survey the use of glass as a modern industrial material in Wright’s architecture and more particularly the art of the stained glass which characterizes Wright among the modernist architects of the early 20th century.
Claude MASSU
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Reetablering av norsk glassmaleri 1900–1913
Kunst og KulturI begynnelsen av 1900-tallet ble produksjonen av monumentale glassmalerier reetablert i Norge. I perioden 1900 til 1913 ble de fire første glassmaleriverkstedene etablert.
Elin Braskerud Tangevold
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Aesthetic art of stained glass in the middle Ages Study (historical analysis)
الاكاديمي, 2017 This paper deals with the role of the clergy in the Church and artists in the emergence of this art, which is represented by an atmosphere of spiritual, aesthetic, artistic, technical and engineering very magnificence and is located in two Find.Chapter ...
Raad mutar majeed
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Les vitraux pour Jérusalem de Chagall : expositions et réception
Interfaces, 2019 In the summer of 1961, Marc Chagall exhibited in Paris twelve stained glass windows designed for the four walls of the Hadassah Medical Center synagogue in Jerusalem.
Christel Scheftsik Naujoks
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Sacrum et Decorum, 2013 The article concerns the influence of Stanisław Wyspiański’s art on the stained-glass design projects of Fryderyk Romańczyk which the latter executed for the churches of Upper Silesia and the Dąbrowa Basin.
Irena Kontny
doaj