Results 131 to 140 of about 3,617,008 (388)
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
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Optimizing Antibody Concentrations for Immunohistochemistry in Neurotrauma Research [PDF]
The Young ResearcherObjective/research question: What primary and secondary antibody concentrations optimize the visualization of immunohistochemical (IHC) stains for antigens prevalent in neurotrauma research?
Shriya Singh
doaj
OBSERVATIONS ON THE MINUTE STRUCTURE OF THE CORTEX OF THE BRAIN AS REVEALED BY THE METHYLENE BLUE AND PEROXIDE OF HYDROGEN METHOD OF STAINING THE TISSUE DIRECT ON ITS REMOVAL FROM THE BODY [PDF]
, 1901 John W. Turner
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Bioagro, 2008 En el complejo Rhizoctonia la morfología hifal y configuración del septo permiten diferenciar los géneros, mientras que las especies pueden ser distinguidas por la condición nuclear y el grosor de hifas “guías” ó la morfometría del teleomorfo.
Luis Cedeño
doaj
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Expression and Significance of TNF-α and NF-κB/p65 in Cutaneous Lichen Planus
Clinical, Cosmetic and Investigational Dermatology, 2022 Jun Fang Chen,1 Xue Mei Zhang,1,2 Kiran Sanjel,1,2 Juan Zhang,2 Cong Ma1 1The Dermatology and Venereology Department, The Affiliated Hospital of Inner Mongolia Minzu University, Tongliao, People’s Republic of China; 2Clinical Medical School, Inner ...
Chen JF +4 more
doaj
The photoelectric measurement of coal dust stains on filter paper [PDF]
, 1951 C. N. Davies, Mary Aylward
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Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
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