Results 61 to 70 of about 2,772,694 (292)

Compartmentalisation and localisation of the translation initiation factor (eIF) 4F complex in normally growing fibroblasts [PDF]

, 2006
Previous observations of association of mRNAs and ribosomes with subcellular structures highlight the importance of localised translation. However, little is known regarding associations between eukaryotic translation initiation factors and cellular ...
Barbarese, Bassell, Bergamini, Biegel, Bonneau, Bushell, Bushell, Caron, Carson, Cervera, Chicurel, Clore, Coldwell, Cowan, Cuesta, Culjkovic, Dang, Delom, Farina, Farmer, Hamill, Hasek, Hill, Hou, Hovland, Hudder, Jansen, Jansen, Jockusch, Kedersha, Kedersha, Kedersha, Kedersha, Kim, Kimball, Kislauskis, Kloc, Latham, Lemieux, Lenk, Lerner, Lerner, Levadoux, Lin, Lindemann, Liu, Mark Willett, Mickleburgh, Micklem, Moore, Moore, Munshi, Murray, Negrutskii, Negrutskii, Negrutskii, Nicchitta, Ornelles, Palacek, Patrick, Pincheira, Prahlad, Pramanik, Prevot, Ramaekers, Shestakova, Simon A. Flint, Simon J. Morley, Smart, Stapulionis, Stapulionis, Svitkin, Svitkin, Taneja, Thoma, Traub, Trombetta, Umikawa, Valouev, van Venrooij, Virginia M. Pain, Wang, Woods   +82 more
core   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Immunocytochemical Phenotyping of Disseminated Tumor Cells in Bone Marrow by uPA Receptor and CK18: Investigation of Sensitivity and Specificity of an Immunogold/Alkaline Phosphatase Double Staining Protocol [PDF]

, 1997
Phenotyping of cytokeratin (CK) 18-positive cells in bone marrow is gaining increasing importance for future prognostic screening of carcinoma patients. Urokinase-type plasminogen activator receptor (uPA-R) is one example of a potential aggressive marker
Allgayer, Heike, Babic, Rudolf, Heiss, Markus Maria, Jauch, Karl-Walter, Riesenberg, Rainer, Schildberg, Friedrich Wilhelm   +5 more
core   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Parental acceptance of the utilization of silver diamine fluoride on their child’s primary and permanent teeth

Patient Preference and Adherence, 2019
Sara M Bagher,1 Heba J Sabbagh,1 Samer M AlJohani,2 Gahida Alharbi,2 Mariam Aldajani,1 Heba Elkhodary3,41Department of Pediatric Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia; 2King Abdulaziz University, Jeddah, Saudi Arabia; 3Department of ...
Bagher SM, Sabbagh HJ, AlJohani SM, Alharbi G, Aldajani M, Elkhodary H   +5 more
doaj  

Evaluation of the efficacy of subgingival irrigation in patients with moderate-to-severe chronic periodontitis otherwise indicated for periodontal flap surgeries

Journal of Indian Society of Periodontology, 2020
Background: In certain medically and physically compromised; and terminally ill patients, periodontal surgery may not be feasible. They need special attention and assistance for their daily plaque control regimens for the management and maintenance of ...
Rajni Jain, Rashi Chaturvedi, Nymphea Pandit, Vishakha Grover, Deborah M Lyle, Ashish Jain   +5 more
doaj   +1 more source

A review of one-step fluorescent cyanoacrylate techniques [PDF]

, 2016
A review of recent research in the use of one-step fluorescent cyanoacrylate techniques is presented. Advantages and disadvantages of such techniques in comparison to two-step processes are discussed.
Deacon, Paul, Farrugia, Kevin J., Stewart, Vanessa   +2 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Molecular Weight Distribution of Proteins Synthesized in Single, Identified Neurons of Aplysia [PDF]

, 1971
Parietovisceral ganglia from Aplysia californica were incubated in medium containing leucine-3H. Single, identified nerve cell somas were isolated from the ganglia, and their proteins extracted and separated by electrophoresis on 5% SDS-polyacrylamide ...
Wilson, David L.
core   +4 more sources