Results 121 to 130 of about 38,124 (276)

Mesoporous Silica Nanoparticles With Customized Drug Ratio/Loading for Effective Treatment of Gemcitabine‐Resistant Pancreatic Tumors

Advanced NanoBiomed Research, EarlyView.
Redox responsive mesoporous silica nanoparticles (MSNs) were engineered to deliver gemcitabine (Gem) and cisplatin (cisPt) at defined ratios to overcome chemoresistance in pancreatic ductal adenocarcinoma (PDAC). Optimized Gem MSNs and Gem cisPt MSNs enhanced cytotoxicity in murine and human Gem resistant models, with select formulations inducing ...
Tamanna Binte Huq, Sudip Kumar Dam, Doaha Awad, Punnya Anil Kumar Jeeja, Farzana Ferdous, Juan L. Vivero‐Escoto   +5 more
wiley   +1 more source

Animal Behavior Responses to Loose and Free Stall Housing

Journal of Dairy Science, 1966
W E, Schmisseur, J L, Albright, W M, Dillon, E W, Kehrberg, W H, Morris   +4 more
openaire   +2 more sources

Functional morphology of the pharyngeal teeth of the ocean sunfish, Mola mola

The Anatomical Record, EarlyView.
Abstract Many fish use a set of pharyngeal jaws in their throat to aid in prey capture and processing, particularly of large or complex prey. In this study—combining dissection, CT scanning, histology, and performance testing—we demonstrate a novel use of pharyngeal teeth in the ocean sunfish (Mola mola), a species for which pharyngeal jaw anatomy had ...
Benjamin Flaum, Michael J. Blumer, Mason N. Dean, Laura J. Ekstrom   +3 more
wiley   +1 more source

Research and application of wing load behavior in stall flight test

Journal of Physics: Conference Series
Abstract This article investigates the variation of aerodynamic loads on wing load measurement profiles during aircraft stall tests and proposes a method for determining the initial stall position and stall time along the wing’s span.
Min Meng, Xian Jiang
openaire   +1 more source

Multi‐method analysis for the three‐dimensional reconstruction of muscle fascicles from DiceCT datasets

The Anatomical Record, EarlyView.
Abstract Muscle architecture is a major determinant of muscle performance and, in mammalian lineages, has been correlated with both feeding ecology and locomotor behaviors. Over the past decade, contrast‐enhanced micro‐CT (DiceCT) has emerged as an alternative to traditional dissection‐based measurement.
Aleksandra Ratkiewicz, Michael C. Granatosky, Cassidy E. Davis, Julia Molnar, Adam Hartstone‐Rose, Edwin Dickinson   +5 more
wiley   +1 more source

Effects of Replacing Alfalfa Hay With Barley Silage in High‐Concentrate Diets: Chewing Behavior, Ruminal Fermentation, Total‐Tract Digestibility, and Milk Production of Dairy Cows in Mid‐Lactation Phase

Animal Research and One Health, EarlyView.
We assessed lactation productivity in dairy cows when replacing alfalfa hay with barley silage. A 50% replacement increased feed intake, whereas total replacement improved nutrient conversion to milk. Barley silage can effectively replace alfalfa hay, enhancing sustainability and resilience in dairy production amid forage quality constraints and market
M. R. Naji‐Zavareh, F. Hashemzadeh, M. Alikhani, M. Khorvash, A. Kahyani, F. Ahmadi   +5 more
wiley   +1 more source

Conditional deep learning model reveals translation elongation determinants during amino acid deprivation. [PDF]

Commun Biol
Nallapareddy MV, Craighero F, Worpenberg L, Naef F, Gobet C, Vandergheynst P.   +5 more
europepmc   +2 more sources

A phase 1 evaluation of inhaled oxytocin: Physiologically‐based pharmacokinetic model informed dosing of a novel heat‐stable oxytocin delivery system

British Journal of Clinical Pharmacology, EarlyView.
Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert, Carl M. J. Kirkpatrick, Rory Marriott, Siladitya Ray Chaudhuri, David Polidori, Bart Remmerie, Michelle P. McIntosh   +6 more
wiley   +1 more source

‘Literal torture’: Vulnerability, resilience and young people's experiences of pressure in physical education

British Educational Research Journal, EarlyView.
Abstract This paper combines vulnerability and resilience theory to explore the pressure young people experience in Physical Education (PE) and sport at secondary school. The theoretical framework was used to understand both how young people experience PE in school and how vulnerability and resilience function interdependently in social contexts like ...
David Littlefair, Michael Jopling
wiley   +1 more source

Making teaching an attractive profession: What are the challenges and opportunities for minority ethnic teachers in England?

British Educational Research Journal, EarlyView.
Abstract This paper explores the challenges and opportunities surrounding the recruitment and retention of minority ethnic teachers in England. Drawing on interview data from 33 teachers and school leaders of diverse ethnic backgrounds, it investigates whether racialised barriers identified in earlier research have shifted in the current context of ...
Antonina Tereshchenko, Feyisa Demie, Stephen Gorard, Yiyang Gao, Beng Huat See, Nadia Siddiqui   +5 more
wiley   +1 more source