Results 181 to 190 of about 1,177,924 (224)
This study shows that patients with gastrointestinal adenocarcinomas can be stratified into six distinct subtypes based on genome‐scale DNA methylation profiling. This stratification, achieved using a robust analytical framework, aligns with established tumor characteristics and holds potential to support prognostication.
Rita Pinto+3 more
wiley +1 more source
Vacuum alignment in composite technicolor standard models [PDF]
Markus A. Luty
openalex +1 more source
Dinaciclib blocks CDK12 activity, leading to downregulation of BRCA1, and probably other proteins involved in homologous recombination, promoting nonhomologous end joining. In this scenario, the presence of ionising radiation triggers a p53‐dependent senescent response that yields increased radiosensitivity. Pan‐cyclin‐dependent‐kinase (CDK) inhibitors
Natalia García Flores+14 more
wiley +1 more source
Role of Criticality Models in ANSI Standards for Nuclear Criticality Safety
J.T. Thomas
openalex +1 more source
No strong coupling regime in the fermion-Higgs sector of the standard model [PDF]
Wolfgang Böck+3 more
openalex +1 more source
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park+6 more
wiley +1 more source
Two-loop heavy-top effects in the Standard Model [PDF]
Riccardo Barbieri+4 more
openalex +1 more source
The mitosis‐related gene SKA1 was among 629 genes consistently dysregulated in OSCC across nine public gene expression datasets. In OSCC cell lines, SKA1 promoted proliferation and migration, enhanced radioresistance, and reduced radiation‐induced senescence.
Alexander Michael Grandits+7 more
wiley +1 more source
One-loop corrections to three-vector-boson vertices in the standard model [PDF]
E.N. Argyres+4 more
openalex +1 more source
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang+10 more
wiley +1 more source