Results 61 to 70 of about 168,186,227 (228)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

The standard of proof the fact of legal presumption of respect

open access: yesLaw: Journal of the University of Latvia, 2022
In democratic countries, the presumption of innocence is one of the pillars of criminal justice, a symbol of respect of the person as the highest social value. It is a fundamental principle of criminal justice, the important warranty of human rights and
Dace Radzeviča
doaj  

Open Meeting of Standard Club

open access: yes, 1914
A program for an open meeting of the Standard Club, held April 21, 1914 at the country club and featuring speeches and ...
Standard Club of Dallas
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

STANDARDS OF PROOF IN THE CONTEXT OF THE MEDICAL CIVIL RESPONSIBILITY

open access: yesRevista Eletrônica de Direito Processual, 2017
This paper discusses the standards of proof, also known as sufficiency models, in the context of the medical civil responsibility. The purpose of this study is to verify, from a doctrinal perception and from a study of cases, what would be the standard ...
Clarissa Diniz Guedes   +1 more
doaj   +1 more source

Minutes of the Standard Club, 1922-1923

open access: yes, 1922
This volume contains the minutes of the Standard Club women's organization of Dallas, Texas from October 1922 through April 1923.
Standard Club of Dallas
core  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Overview of standard and technology development of underground explosion-proof electrical equipment

open access: yesGong-kuang zidonghua, 2015
The paper summarized coal mine underground explosion-proof electrical technique and its development, emphatically introduced the actualities and development trend of coal mine underground explosion-proof electrical standards, analyzed and studied the ...
GAO Peng   +3 more
doaj   +1 more source

[Minutes of the Standard Club, 1886, 1887, 1888, 1889]

open access: yes, 1886
This volume contains the minutes of the meetings of the Standard Club women's organization of Dallas, Texas from 1886 through 1889. Also included are newspaper clippings, programs, and ephemera related to the Standard Club from the 1920s and 1930s.
Standard Club of Dallas
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

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