Results 51 to 60 of about 2,469,574 (283)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The Standard of Proof in Criminal Proceedings: the Threshold to Prove Guilt under Ethiopian Law
Mizan Law Review, 2015 The standard of proof plays a vital role in the process of administration of justice. In criminal proceedings, the standard stipulates the degree to which the party who has the burden of proof needs to establish the facts constituting the elements of ...
HA Zemichael
doaj +1 more source
A New Proof of the Expected Frequency Spectrum under the Standard Neutral Model. [PDF]
PLoS ONE, 2015 The sample frequency spectrum is an informative and frequently employed approach for summarizing DNA variation data. Under the standard neutral model the expectation of the sample frequency spectrum has been derived by at least two distinct approaches ...
Richard R Hudson
doaj +1 more source
Implementation and Optimization of Zero-Knowledge Proof Circuit Based on Hash Function SM3
Sensors, 2022 With the increasing demand for privacy protection in the blockchain, the universal zero-knowledge proof protocol has been developed and widely used. Because hash function is an important cryptographic primitive in a blockchain, the zero-knowledge proof ...
Yang Yang +7 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Rules of Proof, Courts, and Incentives [PDF]
We analyze the design of legal principles and procedures for court decision-making in civil litigation. The objective is the provision of appropriate incentives for potential tort-feasors to exert care, when evidence about care is imperfect and may be ...
Claude Fluet, Dominique Demougin
core +3 more sources
Switching between standard coral reef benthic monitoring protocols is complicated: proof of concept [PDF]
PeerJ, 2019 Monitoring the state of coral reefs is necessary to identify drivers of change and assess effectiveness of management actions. There are several widely-used survey methods, each of which is likely to exhibit different biases that should be quantified if ...
Henri Vallès +2 more
doaj +2 more sources
Revstat Statistical Journal, 2021 Three conjectures on the standard deviation, skewness and kurtosis of the shifted Gompertz distribution, as the shape parameter increases to +∞, are proved. In this regard, the exponential integral function and polygamma functions are used in the proofs.
Fernando Jiménez Torres
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Malaysian Journal of Syariah and LawIn criminal litigation, evidence plays a very significant role in ensuring that justice is delivered. Nevertheless, justice cannot be achieved without the correct application of standard of proof.
Suhaizad Saifuddin +4 more
doaj +1 more source