Results 31 to 40 of about 168,186,227 (228)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

INTERNAL CONVICTION OR THE STANDARD OF PROOF?

open access: yesПравовое государство: теория и практика
The article, devoted in general to evidence in criminal proceedings, focuses on the problem of standards of proof and their role in ensuring the fairness of court decisions.
MASHOVETS Asiia Okeanovna
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

“POST-INVESTIGATIVE” FAMILIARISATION WITH CRIMINAL CASE MATERIALS IN THE CONTEXT OF BALANCING PUBLIC AND PRIVATE INTERESTS

open access: yesПравовое государство: теория и практика
The article, devoted in general to evidence in criminal proceedings, focuses on the problem of standards of proof and their role in ensuring the fairness of court decisions.
ROSSINSKY Sergey Borisovich
doaj   +1 more source

VOL. 2011, 4(5)Polish Antitrust Experience with Hub-and-Spoke Conspiracies [PDF]

open access: yesYearbook of Antitrust and Regulatory Studies, 2011
A hub-and-spoke conspiracy involves an exchange of confidential information primarily concerning future prices. The exchange takes place generally between competing distributors via a common supplier but a reverse relationship is also possible.
Antoni Bolecki
doaj  

General Observations on the Iran-United States Claims Tribunal and a Review of the Tribunal’s Jurisprudence on Arbitration Procedure [PDF]

open access: yesIranian Journal of International and Comparative Law
This article aims to address theoretical and practical issues arising from the author’s "lived experience" in dealing with the developments and intricacies of international arbitration, with a particular focus on experiences related to the Iran-United ...
Jamal Seifi
doaj   +1 more source

A New Proof of the Expected Frequency Spectrum under the Standard Neutral Model. [PDF]

open access: yesPLoS ONE, 2015
The sample frequency spectrum is an informative and frequently employed approach for summarizing DNA variation data. Under the standard neutral model the expectation of the sample frequency spectrum has been derived by at least two distinct approaches ...
Richard R Hudson
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The Standard of Proof in Criminal Proceedings: the Threshold to Prove Guilt under Ethiopian Law

open access: yesMizan Law Review, 2015
The standard of proof plays a vital role in the process of administration of justice. In criminal proceedings, the standard stipulates the degree to which the party who has the burden of proof needs to establish the facts constituting the elements of ...
HA Zemichael
doaj   +1 more source

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