Results 41 to 50 of about 2,469,574 (283)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
General Observations on the Iran-United States Claims Tribunal and a Review of the Tribunal’s Jurisprudence on Arbitration Procedure [PDF]
This article aims to address theoretical and practical issues arising from the author’s "lived experience" in dealing with the developments and intricacies of international arbitration, with a particular focus on experiences related to the Iran-United ...
Jamal Seifi
doaj +1 more source
The Criminalization of Immigration and Intellectual Disability in the United States
Public attitudes, negative stereotypes, and stigma are essential to cultural narratives about the membership status of people with intellectual disability and people who have immigrated to the United States.
Lauren A. Ricciardelli +2 more
doaj +1 more source
A Note on the Identifiability of Generalized Linear Mixed Models [PDF]
I present here a simple proof that, under general regularity conditions, the standard parametrization of generalized linear mixed model is identifiable.
Labouriau, Rodrigo
core
The problem with the geometric discord
We argue that the geometric discord introduced in [B. Dakic, V. Vedral, and C. Brukner, Phys. Rev. Lett. 105, 190502 (2010)] is not a good measure for the quantumness of correlations, as it can increase even under trivial local reversible operations of ...
Piani, Marco
core +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
The article, devoted in general to evidence in criminal proceedings, focuses on the problem of standards of proof and their role in ensuring the fairness of court decisions.
ROSSINSKY Sergey Borisovich
doaj +1 more source
Proof-graphs for Minimal Implicational Logic
It is well-known that the size of propositional classical proofs can be huge. Proof theoretical studies discovered exponential gaps between normal or cut free proofs and their respective non-normal proofs.
Gordeev, Lew +2 more
core +2 more sources
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Deformation of LeBrun's ALE metrics with negative mass
In this article we investigate deformations of a scalar-flat K\"ahler metric on the total space of complex line bundles over CP^1 constructed by C. LeBrun.
A. Kovalev +22 more
core +1 more source

